Hydrogen-bonded supramolecular structures of three related 4-(5-nitro-2-furyl)-1,4-dihydropyridines

A  Quesada; J  Arguello; J A  Squella; J L  Wardell; J N  Low; C  Glidewell

doi:10.1107/S0108270105037753

Hydrogen-bonded supramolecular structures of three related 4-(5-nitro-2-furyl)-1,4-dihydropyridines

A Quesada, J Arguello, J A Squella, J L Wardell, J N Low, C Glidewell

School of Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

In ethyl 5-cyano-2,6-dimethyl-4-(5-nitro-2-furyl)-1,4-dihydropyridine-3-carboxylate, C15H15N3O5, the molecules are linked into chains by a single N-H (...) O hydrogen bond. The molecules in diethyl 2,6-dimethyl-4-(5-nitro-2-furyl)-1,4-dihydropyridine-3,5-dicarboxylate, C17H20N2O7, are linked by a combination of one N-H (...) O hydrogen bond and two CH (...) O hydrogen bonds into sheets built from equal numbers of R-2(2)(17) and R-4(4)(18) rings. In 2,6-dimethyl-4-(5-nitro-2-furyl)1,4-dihydropyridine-3,5-dicarbonitrile, C13H10N4O3, the molecules are linked by a combination of a three-centre NH (...) (O)(2) hydrogen bond and two independent two-centre C-H (...) O hydrogen bonds into complex sheets containing four types of ring.

Original language	English
Number of pages	5
Journal	Acta Crystallographica Section C-Crystal Structure Communications
Volume	62
DOIs	https://doi.org/10.1107/S0108270105037753
Publication status	Published - Jan 2006

Keywords

TRYPANOSOMA-CRUZI
1,4-DIHYDROPYRIDINE
DERIVATIVES
ANTAGONISTS

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@article{4f1a7966f4a7415696f67a05f9e5cc27,

title = "Hydrogen-bonded supramolecular structures of three related 4-(5-nitro-2-furyl)-1,4-dihydropyridines",

abstract = "In ethyl 5-cyano-2,6-dimethyl-4-(5-nitro-2-furyl)-1,4-dihydropyridine-3-carboxylate, C15H15N3O5, the molecules are linked into chains by a single N-H (...) O hydrogen bond. The molecules in diethyl 2,6-dimethyl-4-(5-nitro-2-furyl)-1,4-dihydropyridine-3,5-dicarboxylate, C17H20N2O7, are linked by a combination of one N-H (...) O hydrogen bond and two CH (...) O hydrogen bonds into sheets built from equal numbers of R-2(2)(17) and R-4(4)(18) rings. In 2,6-dimethyl-4-(5-nitro-2-furyl)1,4-dihydropyridine-3,5-dicarbonitrile, C13H10N4O3, the molecules are linked by a combination of a three-centre NH (...) (O)(2) hydrogen bond and two independent two-centre C-H (...) O hydrogen bonds into complex sheets containing four types of ring.",

keywords = "TRYPANOSOMA-CRUZI, 1,4-DIHYDROPYRIDINE, DERIVATIVES, ANTAGONISTS",

author = "A Quesada and J Arguello and Squella, {J A} and Wardell, {J L} and Low, {J N} and C Glidewell",

year = "2006",

month = jan,

doi = "10.1107/S0108270105037753",

language = "English",

volume = "62",

journal = "Acta Crystallographica Section C-Crystal Structure Communications",

issn = "1600-5759",

publisher = "International Union of Crystallography",

}

TY - JOUR

T1 - Hydrogen-bonded supramolecular structures of three related 4-(5-nitro-2-furyl)-1,4-dihydropyridines

AU - Quesada, A

AU - Arguello, J

AU - Squella, J A

AU - Wardell, J L

AU - Low, J N

AU - Glidewell, C

PY - 2006/1

Y1 - 2006/1

N2 - In ethyl 5-cyano-2,6-dimethyl-4-(5-nitro-2-furyl)-1,4-dihydropyridine-3-carboxylate, C15H15N3O5, the molecules are linked into chains by a single N-H (...) O hydrogen bond. The molecules in diethyl 2,6-dimethyl-4-(5-nitro-2-furyl)-1,4-dihydropyridine-3,5-dicarboxylate, C17H20N2O7, are linked by a combination of one N-H (...) O hydrogen bond and two CH (...) O hydrogen bonds into sheets built from equal numbers of R-2(2)(17) and R-4(4)(18) rings. In 2,6-dimethyl-4-(5-nitro-2-furyl)1,4-dihydropyridine-3,5-dicarbonitrile, C13H10N4O3, the molecules are linked by a combination of a three-centre NH (...) (O)(2) hydrogen bond and two independent two-centre C-H (...) O hydrogen bonds into complex sheets containing four types of ring.

AB - In ethyl 5-cyano-2,6-dimethyl-4-(5-nitro-2-furyl)-1,4-dihydropyridine-3-carboxylate, C15H15N3O5, the molecules are linked into chains by a single N-H (...) O hydrogen bond. The molecules in diethyl 2,6-dimethyl-4-(5-nitro-2-furyl)-1,4-dihydropyridine-3,5-dicarboxylate, C17H20N2O7, are linked by a combination of one N-H (...) O hydrogen bond and two CH (...) O hydrogen bonds into sheets built from equal numbers of R-2(2)(17) and R-4(4)(18) rings. In 2,6-dimethyl-4-(5-nitro-2-furyl)1,4-dihydropyridine-3,5-dicarbonitrile, C13H10N4O3, the molecules are linked by a combination of a three-centre NH (...) (O)(2) hydrogen bond and two independent two-centre C-H (...) O hydrogen bonds into complex sheets containing four types of ring.

KW - TRYPANOSOMA-CRUZI

KW - 1,4-DIHYDROPYRIDINE

KW - DERIVATIVES

KW - ANTAGONISTS

U2 - 10.1107/S0108270105037753

DO - 10.1107/S0108270105037753

M3 - Article

SN - 1600-5759

VL - 62

JO - Acta Crystallographica Section C-Crystal Structure Communications

JF - Acta Crystallographica Section C-Crystal Structure Communications

ER -

Hydrogen-bonded supramolecular structures of three related 4-(5-nitro-2-furyl)-1,4-dihydropyridines

Abstract

Keywords

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