Hydrogen-bonded supramolecular structures of three related 4-(5-nitro-2-furyl)-1,4-dihydropyridines

A Quesada, J Arguello, J A Squella, J L Wardell, J N Low, C Glidewell

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

In ethyl 5-cyano-2,6-dimethyl-4-(5-nitro-2-furyl)-1,4-dihydropyridine-3-carboxylate, C15H15N3O5, the molecules are linked into chains by a single N-H (...) O hydrogen bond. The molecules in diethyl 2,6-dimethyl-4-(5-nitro-2-furyl)-1,4-dihydropyridine-3,5-dicarboxylate, C17H20N2O7, are linked by a combination of one N-H (...) O hydrogen bond and two CH (...) O hydrogen bonds into sheets built from equal numbers of R-2(2)(17) and R-4(4)(18) rings. In 2,6-dimethyl-4-(5-nitro-2-furyl)1,4-dihydropyridine-3,5-dicarbonitrile, C13H10N4O3, the molecules are linked by a combination of a three-centre NH (...) (O)(2) hydrogen bond and two independent two-centre C-H (...) O hydrogen bonds into complex sheets containing four types of ring.

Original languageEnglish
Number of pages5
JournalActa Crystallographica Section C-Crystal Structure Communications
Volume62
DOIs
Publication statusPublished - Jan 2006

Keywords

  • TRYPANOSOMA-CRUZI
  • 1,4-DIHYDROPYRIDINE
  • DERIVATIVES
  • ANTAGONISTS

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