Human Immunodeficiency Virus Type 1-Related Pulmonary Mycobacterium xenopi Infection: A Need to Treat?

L. Kerbiriou, A. Ustianowski, M. A. Johnson, S. H. Gillespie, R. F. Miller, M. C.I. Lipman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

We report treatment decisions and outcomes for 20 patients who were infected with human immunodeficiency virus type 1 (HIV-1) and were receiving highly active antiretroviral therapy (HAART) who had respiratory symptoms and from whom Mycobacterium xenopi was isolated. All patients also had coexisting pulmonary pathologic conditions. The median blood T cell CD4 count was 37 cells/μL (range, 2-480 cells/μL). Fifteen of 20 patients received no antimycobacterial therapy and remain healthy after a median of ∼4 years of follow-up, and 2 patients required treatment specifically for M. xenopi infection, both showing clinical improvement. We conclude that pulmonary M. xenopi isolation in HIV-1 patients receiving HAART does not usually require specific treatment.

Original languageEnglish
Pages (from-to)1250-1254
Number of pages5
JournalClinical Infectious Diseases
Volume37
Issue number9
DOIs
Publication statusPublished - 1 Nov 2003

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