Holding it together: chromatin in the archaea

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Abstract

Recently, several advances have been made in the understanding of the form and function of archaeal chromatin. Remarkable parallels can be drawn between the structure and modification of chromatin components in the archaeal and the eukaryotic domains of life. Indeed, it now appears that key components of the hugely complex eukaryotic chromatin regulatory machinery were established before the divergence of the archaeal and eukaryotic lineages.

Original languageEnglish
Pages (from-to)621-626
Number of pages6
JournalTrends in Genetics
Volume18
Publication statusPublished - Dec 2002

Keywords

  • HISTONE-LIKE PROTEIN
  • SUPERCOILED DNA MINICIRCLES
  • POLYMERASE-II HOLOENZYME
  • METHANOTHERMUS-FERVIDUS
  • CRYSTAL-STRUCTURE
  • SULFOLOBUS-ACIDOCALDARIUS
  • (H3-H4)(2) TETRAMER
  • BINDING PROTEINS
  • MC1
  • HMF

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