High iso aldehyde selectivity in the hydroformylation of short-chain alkenes

Leo Iu; José A. Fuentes; Mesfin Janka; Kevin J. Fontenot; Matthew L. Clarke

doi:10.1002/anie.201811888

High iso aldehyde selectivity in the hydroformylation of short-chain alkenes

Leo Iu, José A. Fuentes, Mesfin Janka, Kevin J. Fontenot, Matthew L. Clarke

Research output: Contribution to journal › Article › peer-review

Abstract

The hydroformylation of propene to give predominantly iso‐butanal has been achieved; class‐leading selectivity is possible even at higher temperatures that deliver fast conversion. Racemic rhodium complexes of bidentate phospholane phosphites derived from tropos‐biphenols and unusual solvent systems are the key to the selectivity observed.

Original language	English
Pages (from-to)	2120-2124
Number of pages	5
Journal	Angewandte Chemie International Edition
Volume	58
Issue number	7
Early online date	18 Jan 2019
DOIs	https://doi.org/10.1002/anie.201811888
Publication status	Published - 11 Feb 2019

Keywords

Enantioselective catalysis
Fluorinated solvents
Hydroformylation
Phosphorus ligands
Rhodium

Access to Document

10.1002/anie.201811888

high branched shortchainfinalv3pdf
Copyright © 2019 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. This work has been made available online in accordance with the publisher’s policies. This is the author created accepted version manuscript following peer review and as such may differ slightly from the final published version. The final published version of this work is available at: https://doi.org/10.1002/anie.201811888
Accepted author manuscript, 670 KB

Enantioselective Carbonylations: New Insights New Catalysts and New Processes using Enantioselective Carbonylations
Clarke, M. (PI) & Buehl, M. (CoI)
EPSRC
1/09/14 → 30/11/17
Project: Standard

Matt Clarke
- mc28st-andrews.acuk
- School of Chemistry - Professor (Research Focused)
- EaSTCHEM
Person: Academic - Research

Underpinning data: High iso aldehyde selectivity in the hydroformylation of short-chain alkenes
Fuentes García, J. A. (Creator), Clarke, M. L. (Creator), Iu, L. (Creator), Janka, M. E. (Creator) & Fontenot, K. J. (Creator), University of St Andrews, 25 Jan 2019
DOI: 10.17630/6ed96377-ab54-4fb3-98c9-d2a5bc4d333e
Dataset

File

Cite this

@article{22bd59a078d8448e8509df66dd6c940c,

title = "High iso aldehyde selectivity in the hydroformylation of short-chain alkenes",

abstract = "The hydroformylation of propene to give predominantly iso‐butanal has been achieved; class‐leading selectivity is possible even at higher temperatures that deliver fast conversion. Racemic rhodium complexes of bidentate phospholane phosphites derived from tropos‐biphenols and unusual solvent systems are the key to the selectivity observed.",

keywords = "Enantioselective catalysis, Fluorinated solvents, Hydroformylation, Phosphorus ligands, Rhodium",

author = "Leo Iu and Fuentes, {Jos{\'e} A.} and Mesfin Janka and Fontenot, {Kevin J.} and Clarke, {Matthew L.}",

note = "The authors thank the Eastman Chemical Company for funding (LI, and later JAF) and permission to publish. The EPSRC (EP/M003868/1) is also acknowledged for funding (JAF). ",

year = "2019",

month = feb,

day = "11",

doi = "10.1002/anie.201811888",

language = "English",

volume = "58",

pages = "2120--2124",

journal = "Angewandte Chemie International Edition",

issn = "1433-7851",

publisher = "John Wiley & Sons, Ltd",

number = "7",

}

TY - JOUR

T1 - High iso aldehyde selectivity in the hydroformylation of short-chain alkenes

AU - Iu, Leo

AU - Fuentes, José A.

AU - Janka, Mesfin

AU - Fontenot, Kevin J.

AU - Clarke, Matthew L.

N1 - The authors thank the Eastman Chemical Company for funding (LI, and later JAF) and permission to publish. The EPSRC (EP/M003868/1) is also acknowledged for funding (JAF).

PY - 2019/2/11

Y1 - 2019/2/11

N2 - The hydroformylation of propene to give predominantly iso‐butanal has been achieved; class‐leading selectivity is possible even at higher temperatures that deliver fast conversion. Racemic rhodium complexes of bidentate phospholane phosphites derived from tropos‐biphenols and unusual solvent systems are the key to the selectivity observed.

AB - The hydroformylation of propene to give predominantly iso‐butanal has been achieved; class‐leading selectivity is possible even at higher temperatures that deliver fast conversion. Racemic rhodium complexes of bidentate phospholane phosphites derived from tropos‐biphenols and unusual solvent systems are the key to the selectivity observed.

KW - Enantioselective catalysis

KW - Fluorinated solvents

KW - Hydroformylation

KW - Phosphorus ligands

KW - Rhodium

U2 - 10.1002/anie.201811888

DO - 10.1002/anie.201811888

M3 - Article

SN - 1433-7851

VL - 58

SP - 2120

EP - 2124

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

IS - 7

ER -

High iso aldehyde selectivity in the hydroformylation of short-chain alkenes

Abstract

Keywords

Access to Document

Fingerprint

Projects

Enantioselective Carbonylations: New Insights New Catalysts and New Processes using Enantioselective Carbonylations

Profiles

Matt Clarke

Datasets

Underpinning data: High iso aldehyde selectivity in the hydroformylation of short-chain alkenes

Cite this