TY - JOUR
T1 - High fear of cancer recurrence in Chinese newly diagnosed cancer patients
AU - Luo, Xian
AU - Li, Wengao
AU - Yang, Yuan
AU - Humphris, Gerald
AU - Zeng, Lijuan
AU - Zhang, Zijun
AU - Garg, Samradhvi
AU - Zhang, Bin
AU - Sun, Hengwen
N1 - Authors thank the President Foundation of Nanfang Hospital, Southern Medical University (2007L001), and the Guangzhou Science and Technology Project (201804010132) for funding the study.
PY - 2020/6/9
Y1 - 2020/6/9
N2 - Background: Fear of cancer recurrence (FCR) is
common among cancer patients and of high clinical relevance. This study
explores the prevalence and correlates of FCR in Chinese newly diagnosed
cancer population.
Methods: This is a multicentre, cross-sectional
study that includes 996 patients with mixed cancer diagnosis. All
recently diagnosed patients completed a questionnaire consisting of the
following: Fear of Progression Questionnaire-Short Form (FoP-Q-SF),
General Anxiety Disorder Questionnaire (GAD-7), and Patient Health
Questionnaire (PHQ-9). Univariate analyses, multivariate logistic
regression analyses, and structural equation modeling (SEM) was
performed to examine the association between tested variables and FCR.
Results: Of the 996 patients, 643 (64.6%) reported high FCR (scored ≥ 34 in the FoP-Q-SF). Chemotherapy (OR = 1.941), Childhood severe illness experience (OR = 2.802), depressive (OR = 1.153), and anxiety (OR = 1.249) symptoms were positively associated with high FCR, while higher monthly income (OR
= 0.592) was negatively associated with high FCR. SEM indicated that
emotional disturbances (anxiety and depression) directly influenced FCR,
while emotional disturbances partly mediated the association between
personal monthly income and FCR.
Conclusion: High FCR is a frequently reported
problem among newly diagnosed cancer patients. Various factors increased
the likelihood of the development of FCR. Flexible psychological
interventions are needed for patients with high FCR.
AB - Background: Fear of cancer recurrence (FCR) is
common among cancer patients and of high clinical relevance. This study
explores the prevalence and correlates of FCR in Chinese newly diagnosed
cancer population.
Methods: This is a multicentre, cross-sectional
study that includes 996 patients with mixed cancer diagnosis. All
recently diagnosed patients completed a questionnaire consisting of the
following: Fear of Progression Questionnaire-Short Form (FoP-Q-SF),
General Anxiety Disorder Questionnaire (GAD-7), and Patient Health
Questionnaire (PHQ-9). Univariate analyses, multivariate logistic
regression analyses, and structural equation modeling (SEM) was
performed to examine the association between tested variables and FCR.
Results: Of the 996 patients, 643 (64.6%) reported high FCR (scored ≥ 34 in the FoP-Q-SF). Chemotherapy (OR = 1.941), Childhood severe illness experience (OR = 2.802), depressive (OR = 1.153), and anxiety (OR = 1.249) symptoms were positively associated with high FCR, while higher monthly income (OR
= 0.592) was negatively associated with high FCR. SEM indicated that
emotional disturbances (anxiety and depression) directly influenced FCR,
while emotional disturbances partly mediated the association between
personal monthly income and FCR.
Conclusion: High FCR is a frequently reported
problem among newly diagnosed cancer patients. Various factors increased
the likelihood of the development of FCR. Flexible psychological
interventions are needed for patients with high FCR.
KW - Cancer
KW - Chinese
KW - Fear of recurrence
KW - Newly diagnosed
KW - Structural equation modeling
UR - https://www.scopus.com/pages/publications/85087041507
U2 - 10.3389/fpsyg.2020.01287
DO - 10.3389/fpsyg.2020.01287
M3 - Article
SN - 1664-1078
VL - 11
JO - Frontiers in Psychology
JF - Frontiers in Psychology
M1 - 1287
ER -