Hadamard randomization: a valid restriction of random permuted blocks

Rosemary Anne Bailey, P. R. Nelson

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

Random permuted blocks can result in treatment imbalance if entry to the trial stops mid-block. This paper presents a restriction of this method of randomization. The restriction avoids severe treatment imbalance but gives unbiased estimators of the treatment difference and its variance.
Original languageEnglish
Pages (from-to)554-560
Number of pages7
JournalBiometrical Journal
Volume45
Publication statusPublished - 2003

Keywords

  • randomization
  • random permuted blocks

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