Grand Challenges in global eye health: a global prioritisation process using Delphi method

Grand Challenges in Global Eye Health study group, Jacqueline Ramke*, Jennifer R. Evans, Esmael Habtamu, Nyawira Mwangi, Juan Carlos Silva, Bonnielin K. Swenor, Nathan Congdon, Hannah B. Faal, Allen Foster, David S. Friedman, Stephen Gichuhi, Jost B. Jonas, Peng T. Khaw, Fatima Kyari, Gudlavalleti V.S. Murthy, Ningli Wang, Tien Y. Wong, Richard Wormald, Mayinuer YusufuHugh Taylor, Serge Resnikoff, Sheila K. West, Matthew J. Burton, Ada Aghaji, Adeyemi T. Adewole, Adrienne Csutak, Ahmad Shah Salam, Ala Paduca, Alain M. Bron, Alastair K. Denniston, Alberto Lazo Legua, Aldiana Halim, Alemayehu Woldeyes Tefera, Alice Mwangi, Alicia J. Jenkins, Amanda Davis, Amel Meddeb-Ouertani, Amina H. Wali, Ana G. Palis, Ana Bastos de Carvalho, Anagha Joshi, Andreas J. Kreis, Andreas Mueller, Andrew Bastawrous, Andrew Cooper, Andrew F. Smith, Andrzej Grzybowski, Gatera Fiston Kitema, Imran A. Khan, Jennifer M. Burr

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background We undertook a Grand Challenges in Global Eye Health prioritisation exercise to identify the key issues that must be addressed to improve eye health in the context of an ageing population, to eliminate persistent inequities in health-care access, and to mitigate widespread resource limitations. 

Methods Drawing on methods used in previous Grand Challenges studies, we used a multi-step recruitment strategy to assemble a diverse panel of individuals from a range of disciplines relevant to global eye health from all regions globally to participate in a three-round, online, Delphi-like, prioritisation process to nominate and rank challenges in global eye health. Through this process, we developed both global and regional priority lists. 

Findings Between Sept 1 and Dec 12, 2019, 470 individuals complete round 1 of the process, of whom 336 completed all three rounds (round 2 between Feb 26 and March 18, 2020, and round 3 between April 2 and April 25, 2020) 156 (46%) of 336 were women, 180 (54%) were men. The proportion of participants who worked in each region ranged from 104 (31%) in sub-Saharan Africa to 21 (6%) in central Europe, eastern Europe, and in central Asia. Of 85 unique challenges identified after round 1, 16 challenges were prioritised at the global level; six focused on detection and treatment of conditions (cataract, refractive error, glaucoma, diabetic retinopathy, services for children and screening for early detection), two focused on addressing shortages in human resource capacity, five on other health service and policy factors (including strengthening policies, integration, health information systems, and budget allocation), and three on improving access to care and promoting equity. 

Interpretation This list of Grand Challenges serves as a starting point for immediate action by funders to guide investment in research and innovation in eye health. It challenges researchers, clinicians, and policy makers to build collaborations to address specific challenges.

Original languageEnglish
Pages (from-to)e31-e41
Number of pages11
JournalThe Lancet Healthy Longevity
Issue number1
Publication statusPublished - 1 Jan 2022


Dive into the research topics of 'Grand Challenges in global eye health: a global prioritisation process using Delphi method'. Together they form a unique fingerprint.

Cite this