Gold-acetonyl complexes: from side-products to valuable synthons

Danila Gasperini; Alba Collado-Martinez; Adrian Gomez Suarez; David Bradford Cordes; Alexandra Martha Zoya Slawin; Steven Patrick Nolan

doi:10.1002/chem.201406543

Gold-acetonyl complexes: from side-products to valuable synthons

Danila Gasperini, Alba Collado-Martinez, Adrian Gomez Suarez, David Bradford Cordes, Alexandra Martha Zoya Slawin, Steven Patrick Nolan

Research output: Contribution to journal › Article › peer-review

Abstract

A new synthetic strategy was devised leading to the formation of complexes, such as [Au(IPr)(CH₂COCH₃)]. The approach capitalizes on the formation of a decomposition product observed in the course of the synthesis of [Au(IPr)(Cl)]. A library of gold acetonyl complexes containing the most common N-heterocyclic carbene (NHC) ligands has been synthesized. These acetonyl complexes are good synthons for the preparation of numerous organogold complexes. Moreover, they have proven to be precatalysts in common gold(I)-catalyzed reactions.

Original language	English
Pages (from-to)	5403-5412
Number of pages	10
Journal	Chemistry - A European Journal
Volume	21
Issue number	14
Early online date	20 Feb 2015
DOIs	https://doi.org/10.1002/chem.201406543
Publication status	Published - 27 Mar 2015

Keywords

Gold
Acetonyl
N-heterocyclic carbene
Organogold complexes
Catalysis
Carbenes
Organogold
Homogeneous catalysis

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10.1002/chem.201406543

Nolan_2015_ChemEUJ_Gold_AM
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This is the accepted version of the following article: Gasperini, D., Collado, A., Goméz-Suárez, A., Cordes, D. B., Slawin, A. M. Z. and Nolan, S. P. (2015), Gold–Acetonyl Complexes: From Side-Products to Valuable Synthons. Chem. Eur. J., which has been published in final form at http://onlinelibrary.wiley.com/doi/10.1002/chem.201406543/abstract
Accepted author manuscript, 1.14 MB

Cite this

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title = "Gold-acetonyl complexes: from side-products to valuable synthons",

abstract = "A new synthetic strategy was devised leading to the formation of complexes, such as [Au(IPr)(CH2COCH3)]. The approach capitalizes on the formation of a decomposition product observed in the course of the synthesis of [Au(IPr)(Cl)]. A library of gold acetonyl complexes containing the most common N-heterocyclic carbene (NHC) ligands has been synthesized. These acetonyl complexes are good synthons for the preparation of numerous organogold complexes. Moreover, they have proven to be precatalysts in common gold(I)-catalyzed reactions.",

keywords = "Gold, Acetonyl , N-heterocyclic carbene, Organogold complexes, Catalysis, Carbenes, Organogold, Homogeneous catalysis",

author = "Danila Gasperini and Alba Collado-Martinez and {Gomez Suarez}, Adrian and Cordes, {David Bradford} and Slawin, {Alexandra Martha Zoya} and Nolan, {Steven Patrick}",

note = "The ERC (Advanced Investigator Award-FUNCAT), EPSRC and Syngenta are gratefully acknowledged for support. Umicore AG is acknowledged for their generous gift of materials. S.P.N. is a Royal Society Wolfson Research Merit Award holder. ",

year = "2015",

month = mar,

day = "27",

doi = "10.1002/chem.201406543",

language = "English",

volume = "21",

pages = "5403--5412",

journal = "Chemistry - A European Journal",

issn = "0947-6539",

publisher = "John Wiley & Sons, Ltd",

number = "14",

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TY - JOUR

T1 - Gold-acetonyl complexes

T2 - from side-products to valuable synthons

AU - Gasperini, Danila

AU - Collado-Martinez, Alba

AU - Gomez Suarez, Adrian

AU - Cordes, David Bradford

AU - Slawin, Alexandra Martha Zoya

AU - Nolan, Steven Patrick

N1 - The ERC (Advanced Investigator Award-FUNCAT), EPSRC and Syngenta are gratefully acknowledged for support. Umicore AG is acknowledged for their generous gift of materials. S.P.N. is a Royal Society Wolfson Research Merit Award holder.

PY - 2015/3/27

Y1 - 2015/3/27

N2 - A new synthetic strategy was devised leading to the formation of complexes, such as [Au(IPr)(CH2COCH3)]. The approach capitalizes on the formation of a decomposition product observed in the course of the synthesis of [Au(IPr)(Cl)]. A library of gold acetonyl complexes containing the most common N-heterocyclic carbene (NHC) ligands has been synthesized. These acetonyl complexes are good synthons for the preparation of numerous organogold complexes. Moreover, they have proven to be precatalysts in common gold(I)-catalyzed reactions.

AB - A new synthetic strategy was devised leading to the formation of complexes, such as [Au(IPr)(CH2COCH3)]. The approach capitalizes on the formation of a decomposition product observed in the course of the synthesis of [Au(IPr)(Cl)]. A library of gold acetonyl complexes containing the most common N-heterocyclic carbene (NHC) ligands has been synthesized. These acetonyl complexes are good synthons for the preparation of numerous organogold complexes. Moreover, they have proven to be precatalysts in common gold(I)-catalyzed reactions.

KW - Gold

KW - Acetonyl

KW - N-heterocyclic carbene

KW - Organogold complexes

KW - Catalysis

KW - Carbenes

KW - Organogold

KW - Homogeneous catalysis

UR - http://onlinelibrary.wiley.com/doi/10.1002/chem.201406543/suppinfo

U2 - 10.1002/chem.201406543

DO - 10.1002/chem.201406543

M3 - Article

SN - 0947-6539

VL - 21

SP - 5403

EP - 5412

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 14

ER -

Gold-acetonyl complexes: from side-products to valuable synthons

Abstract

Keywords

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FUNCAT: EU FP7 ERC Advanced Grant - FUNCAT - Fundamental Studies in Organometallic Chemistry and Homogeneous Catalysis