Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

Pierre Abad; Jerome Gouzy; Jean-Marc Aury; Philippe Castagnone-Sereno; Etienne G. J. Danchin; Emeline Deleury; Laetitia Perfus-Barbeoch; Veronique Anthouard; Francois Artiguenave; Vivian C. Blok; Marie-Cecile Caillaud; Pedro M. Coutinho; Corinne Dasilva; Francesca De Luca; Florence Deau; Magali Esquibet; Timothe Flutre; Jared V. Goldstone; Noureddine Hamamouch; Tarek Hewezi; Olivier Jaillon; Claire Jubin; Paola Leonetti; Marc Magliano; Tom R. Maier; Gabriel V. Markov; Paul McVeigh; Graziano Pesole; Julie Poulain; Marc Robinson-Rechavi; Erika Sallet; Beatrice Segurens; Delphine Steinbach; Tom Tytgat; Edgardo Ugarte; Cyril van Ghelder; Pasqua Veronico; Thomas J. Baum; Mark Blaxter; Teresa Bleve-Zacheo; Eric L. Davis; Jonathan J. Ewbank; Bruno Favery; Eric Grenier; Bernard Henrissat; John T. Jones; Vincent Laudet; Aaron G. Maule; Hadi Quesneville; Marie-Noelle Rosso; Thomas Schiex; Geert Smant; Jean Weissenbach; Patrick Wincker

doi:10.1038/nbt.1482

Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

Pierre Abad^*, Jerome Gouzy, Jean-Marc Aury, Philippe Castagnone-Sereno, Etienne G. J. Danchin, Emeline Deleury, Laetitia Perfus-Barbeoch, Veronique Anthouard, Francois Artiguenave, Vivian C. Blok, Marie-Cecile Caillaud, Pedro M. Coutinho, Corinne Dasilva, Francesca De Luca, Florence Deau, Magali Esquibet, Timothe Flutre, Jared V. Goldstone, Noureddine Hamamouch, Tarek HeweziOlivier Jaillon, Claire Jubin, Paola Leonetti, Marc Magliano, Tom R. Maier, Gabriel V. Markov, Paul McVeigh, Graziano Pesole, Julie Poulain, Marc Robinson-Rechavi, Erika Sallet, Beatrice Segurens, Delphine Steinbach, Tom Tytgat, Edgardo Ugarte, Cyril van Ghelder, Pasqua Veronico, Thomas J. Baum, Mark Blaxter, Teresa Bleve-Zacheo, Eric L. Davis, Jonathan J. Ewbank, Bruno Favery, Eric Grenier, Bernard Henrissat, John T. Jones, Vincent Laudet, Aaron G. Maule, Hadi Quesneville, Marie-Noelle Rosso, Thomas Schiex, Geert Smant, Jean Weissenbach, Patrick Wincker

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.

Original language	English
Pages (from-to)	909-915
Number of pages	7
Journal	Nature Biotechnology
Volume	26
Issue number	8
DOIs	https://doi.org/10.1038/nbt.1482
Publication status	Published - Aug 2008

Keywords

ROOT-KNOT NEMATODES
CAENORHABDITIS-ELEGANS
PHYTOPATHOGENIC BACTERIA
BDELLOID ROTIFERS
GENES
PROTEIN
CLONING
IDENTIFICATION
EXPRESSION
PREDICTION

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10.1038/nbt.1482

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Abad, P., Gouzy, J., Aury, J.-M., Castagnone-Sereno, P., Danchin, E. G. J., Deleury, E., Perfus-Barbeoch, L., Anthouard, V., Artiguenave, F., Blok, V. C., Caillaud, M.-C., Coutinho, P. M., Dasilva, C., De Luca, F., Deau, F., Esquibet, M., Flutre, T., Goldstone, J. V., Hamamouch, N., ... Wincker, P. (2008). Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita. Nature Biotechnology, 26(8), 909-915. https://doi.org/10.1038/nbt.1482

@article{6b0ee1806e0d44368ee433e491400a9b,

title = "Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita",

abstract = "Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.",

keywords = "ROOT-KNOT NEMATODES, CAENORHABDITIS-ELEGANS, PHYTOPATHOGENIC BACTERIA, BDELLOID ROTIFERS, GENES, PROTEIN, CLONING, IDENTIFICATION, EXPRESSION, PREDICTION",

author = "Pierre Abad and Jerome Gouzy and Jean-Marc Aury and Philippe Castagnone-Sereno and Danchin, {Etienne G. J.} and Emeline Deleury and Laetitia Perfus-Barbeoch and Veronique Anthouard and Francois Artiguenave and Blok, {Vivian C.} and Marie-Cecile Caillaud and Coutinho, {Pedro M.} and Corinne Dasilva and {De Luca}, Francesca and Florence Deau and Magali Esquibet and Timothe Flutre and Goldstone, {Jared V.} and Noureddine Hamamouch and Tarek Hewezi and Olivier Jaillon and Claire Jubin and Paola Leonetti and Marc Magliano and Maier, {Tom R.} and Markov, {Gabriel V.} and Paul McVeigh and Graziano Pesole and Julie Poulain and Marc Robinson-Rechavi and Erika Sallet and Beatrice Segurens and Delphine Steinbach and Tom Tytgat and Edgardo Ugarte and {van Ghelder}, Cyril and Pasqua Veronico and Baum, {Thomas J.} and Mark Blaxter and Teresa Bleve-Zacheo and Davis, {Eric L.} and Ewbank, {Jonathan J.} and Bruno Favery and Eric Grenier and Bernard Henrissat and Jones, {John T.} and Vincent Laudet and Maule, {Aaron G.} and Hadi Quesneville and Marie-Noelle Rosso and Thomas Schiex and Geert Smant and Jean Weissenbach and Patrick Wincker",

year = "2008",

month = aug,

doi = "10.1038/nbt.1482",

language = "English",

volume = "26",

pages = "909--915",

journal = "Nature Biotechnology",

issn = "1087-0156",

publisher = "Nature publishing group",

number = "8",

}

Abad, P, Gouzy, J, Aury, J-M, Castagnone-Sereno, P, Danchin, EGJ, Deleury, E, Perfus-Barbeoch, L, Anthouard, V, Artiguenave, F, Blok, VC, Caillaud, M-C, Coutinho, PM, Dasilva, C, De Luca, F, Deau, F, Esquibet, M, Flutre, T, Goldstone, JV, Hamamouch, N, Hewezi, T, Jaillon, O, Jubin, C, Leonetti, P, Magliano, M, Maier, TR, Markov, GV, McVeigh, P, Pesole, G, Poulain, J, Robinson-Rechavi, M, Sallet, E, Segurens, B, Steinbach, D, Tytgat, T, Ugarte, E, van Ghelder, C, Veronico, P, Baum, TJ, Blaxter, M, Bleve-Zacheo, T, Davis, EL, Ewbank, JJ, Favery, B, Grenier, E, Henrissat, B, Jones, JT, Laudet, V, Maule, AG, Quesneville, H, Rosso, M-N, Schiex, T, Smant, G, Weissenbach, J & Wincker, P 2008, 'Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita', Nature Biotechnology, vol. 26, no. 8, pp. 909-915. https://doi.org/10.1038/nbt.1482

TY - JOUR

T1 - Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

AU - Abad, Pierre

AU - Gouzy, Jerome

AU - Aury, Jean-Marc

AU - Castagnone-Sereno, Philippe

AU - Danchin, Etienne G. J.

AU - Deleury, Emeline

AU - Perfus-Barbeoch, Laetitia

AU - Anthouard, Veronique

AU - Artiguenave, Francois

AU - Blok, Vivian C.

AU - Caillaud, Marie-Cecile

AU - Coutinho, Pedro M.

AU - Dasilva, Corinne

AU - De Luca, Francesca

AU - Deau, Florence

AU - Esquibet, Magali

AU - Flutre, Timothe

AU - Goldstone, Jared V.

AU - Hamamouch, Noureddine

AU - Hewezi, Tarek

AU - Jaillon, Olivier

AU - Jubin, Claire

AU - Leonetti, Paola

AU - Magliano, Marc

AU - Maier, Tom R.

AU - Markov, Gabriel V.

AU - McVeigh, Paul

AU - Pesole, Graziano

AU - Poulain, Julie

AU - Robinson-Rechavi, Marc

AU - Sallet, Erika

AU - Segurens, Beatrice

AU - Steinbach, Delphine

AU - Tytgat, Tom

AU - Ugarte, Edgardo

AU - van Ghelder, Cyril

AU - Veronico, Pasqua

AU - Baum, Thomas J.

AU - Blaxter, Mark

AU - Bleve-Zacheo, Teresa

AU - Davis, Eric L.

AU - Ewbank, Jonathan J.

AU - Favery, Bruno

AU - Grenier, Eric

AU - Henrissat, Bernard

AU - Jones, John T.

AU - Laudet, Vincent

AU - Maule, Aaron G.

AU - Quesneville, Hadi

AU - Rosso, Marie-Noelle

AU - Schiex, Thomas

AU - Smant, Geert

AU - Weissenbach, Jean

AU - Wincker, Patrick

PY - 2008/8

Y1 - 2008/8

N2 - Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.

AB - Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall-degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.

KW - ROOT-KNOT NEMATODES

KW - CAENORHABDITIS-ELEGANS

KW - PHYTOPATHOGENIC BACTERIA

KW - BDELLOID ROTIFERS

KW - GENES

KW - PROTEIN

KW - CLONING

KW - IDENTIFICATION

KW - EXPRESSION

KW - PREDICTION

U2 - 10.1038/nbt.1482

DO - 10.1038/nbt.1482

M3 - Article

SN - 1087-0156

VL - 26

SP - 909

EP - 915

JO - Nature Biotechnology

JF - Nature Biotechnology

IS - 8

ER -

Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

Abstract

Keywords

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