Genetic and epigenetic analyses of MBD3 in colon and lung cancer

Y Zhu; D J Harrison; S A Bader

doi:10.1038/sj.bjc.6601776

Genetic and epigenetic analyses of MBD3 in colon and lung cancer

Y Zhu, D J Harrison, S A Bader

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

MBD3: is a member of the methyl-CpG-binding domain family and is located on chromosome 19p13.3, a region of loss of heterozygosity in colon and lung cancers. We therefore screened samples for abnormalities in MBD3. Our results indicate that MBD3 is not a major target of genetic and epigenetic alteration in these cancers.

Original language	English
Pages (from-to)	1972-1975
Number of pages	4
Journal	British Journal of Cancer
Volume	90
Issue number	10
Early online date	13 Apr 2004
DOIs	https://doi.org/10.1038/sj.bjc.6601776
Publication status	Published - 17 May 2004

Keywords

MBD3
Colon cancer
Lung cancer
Mutation
Methylation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/sj.bjc.6601776

zhu2004bjc1972
Copyright 2004 Cancer Research UK. From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
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Cite this

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abstract = "MBD3: is a member of the methyl-CpG-binding domain family and is located on chromosome 19p13.3, a region of loss of heterozygosity in colon and lung cancers. We therefore screened samples for abnormalities in MBD3. Our results indicate that MBD3 is not a major target of genetic and epigenetic alteration in these cancers.",

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AU - Harrison, D J

AU - Bader, S A

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AB - MBD3: is a member of the methyl-CpG-binding domain family and is located on chromosome 19p13.3, a region of loss of heterozygosity in colon and lung cancers. We therefore screened samples for abnormalities in MBD3. Our results indicate that MBD3 is not a major target of genetic and epigenetic alteration in these cancers.

KW - MBD3

KW - Colon cancer

KW - Lung cancer

KW - Mutation

KW - Methylation

UR - http://www.nature.com/bjc/journal/v90/n10/full/6601776a.html

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Genetic and epigenetic analyses of MBD3 in colon and lung cancer

Abstract

Keywords

UN SDGs

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