FXR activation aids fibrinolysis: targeting PAI-1 in obesity

Alan J. Stewart

doi:10.1182/blood.2025030984

FXR activation aids fibrinolysis: targeting PAI-1 in obesity

Research output: Contribution to journal › Comment/debate › peer-review

Original language	English
Pages (from-to)	2381-2382
Number of pages	2
Journal	Blood
Volume	146
Issue number	20
DOIs	https://doi.org/10.1182/blood.2025030984
Publication status	Published - 13 Nov 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Farnesoid-X-receptor
Plasminogen activator inhibitor-1
Bile acids
Animal models
Fibrinolysis

Access to Document

10.1182/blood.2025030984

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Cite this

@article{2edbd66e4c0e453fb5c99faefc736533,

title = "FXR activation aids fibrinolysis: targeting PAI-1 in obesity",

keywords = "Farnesoid-X-receptor, Plasminogen activator inhibitor-1, Bile acids, Animal models, Fibrinolysis",

author = "Stewart, \{Alan J.\}",

note = "Conflict-of-interest disclosure: The author declares no competing financial interests. ",

year = "2025",

month = nov,

day = "13",

doi = "10.1182/blood.2025030984",

language = "English",

volume = "146",

pages = "2381--2382",

journal = "Blood",

issn = "0006-4971",

publisher = "Elsevier",

number = "20",

}

TY - JOUR

T1 - FXR activation aids fibrinolysis

T2 - targeting PAI-1 in obesity

AU - Stewart, Alan J.

N1 - Conflict-of-interest disclosure: The author declares no competing financial interests.

PY - 2025/11/13

Y1 - 2025/11/13

KW - Farnesoid-X-receptor

KW - Plasminogen activator inhibitor-1

KW - Bile acids

KW - Animal models

KW - Fibrinolysis

U2 - 10.1182/blood.2025030984

DO - 10.1182/blood.2025030984

M3 - Comment/debate

SN - 0006-4971

VL - 146

SP - 2381

EP - 2382

JO - Blood

JF - Blood

IS - 20

ER -