Function of minor polypeptides in foot-and-mouth disease virus and poliovirus

J. F E Newman; P. G. Piatti; M. D. Ryan; F. Brown

doi:10.1016/0966-842X(94)90655-6

Function of minor polypeptides in foot-and-mouth disease virus and poliovirus

J. F E Newman^*, P. G. Piatti, M. D. Ryan, F. Brown

^*Corresponding author for this work

School of Biology

Research output: Contribution to journal › Short survey › peer-review

Abstract

Foot-and-mouth disease virus and poliovirus each contain several minor polypeptides, in addition to the four structural proteins. One of these, the viral RNA polymerase, can also act as a nuclease, hydrolysing the RNA and thus destroying viral infectivity. It is tightly bound to the RNA and may be the packaging signal for assembly of the particle.

Original language	English
Pages (from-to)	494-496
Number of pages	3
Journal	Trends in Microbiology
Volume	2
Issue number	12
DOIs	https://doi.org/10.1016/0966-842X(94)90655-6
Publication status	Published - 16 Dec 1994

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0966-842X(94)90655-6

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title = "Function of minor polypeptides in foot-and-mouth disease virus and poliovirus",

abstract = "Foot-and-mouth disease virus and poliovirus each contain several minor polypeptides, in addition to the four structural proteins. One of these, the viral RNA polymerase, can also act as a nuclease, hydrolysing the RNA and thus destroying viral infectivity. It is tightly bound to the RNA and may be the packaging signal for assembly of the particle.",

author = "Newman, {J. F E} and Piatti, {P. G.} and Ryan, {M. D.} and F. Brown",

year = "1994",

month = dec,

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doi = "10.1016/0966-842X(94)90655-6",

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journal = "Trends in Microbiology",

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T1 - Function of minor polypeptides in foot-and-mouth disease virus and poliovirus

AU - Newman, J. F E

AU - Piatti, P. G.

AU - Ryan, M. D.

AU - Brown, F.

PY - 1994/12/16

Y1 - 1994/12/16

N2 - Foot-and-mouth disease virus and poliovirus each contain several minor polypeptides, in addition to the four structural proteins. One of these, the viral RNA polymerase, can also act as a nuclease, hydrolysing the RNA and thus destroying viral infectivity. It is tightly bound to the RNA and may be the packaging signal for assembly of the particle.

AB - Foot-and-mouth disease virus and poliovirus each contain several minor polypeptides, in addition to the four structural proteins. One of these, the viral RNA polymerase, can also act as a nuclease, hydrolysing the RNA and thus destroying viral infectivity. It is tightly bound to the RNA and may be the packaging signal for assembly of the particle.

UR - http://www.scopus.com/inward/record.url?scp=0028170492&partnerID=8YFLogxK

U2 - 10.1016/0966-842X(94)90655-6

DO - 10.1016/0966-842X(94)90655-6

M3 - Short survey

C2 - 7889327

AN - SCOPUS:0028170492

SN - 0966-842X

VL - 2

SP - 494

EP - 496

JO - Trends in Microbiology

JF - Trends in Microbiology

IS - 12

ER -

Function of minor polypeptides in foot-and-mouth disease virus and poliovirus

Abstract

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