Function of minor polypeptides in foot-and-mouth disease virus and poliovirus

J. F E Newman*, P. G. Piatti, M. D. Ryan, F. Brown

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

9 Citations (Scopus)

Abstract

Foot-and-mouth disease virus and poliovirus each contain several minor polypeptides, in addition to the four structural proteins. One of these, the viral RNA polymerase, can also act as a nuclease, hydrolysing the RNA and thus destroying viral infectivity. It is tightly bound to the RNA and may be the packaging signal for assembly of the particle.

Original languageEnglish
Pages (from-to)494-496
Number of pages3
JournalTrends in Microbiology
Volume2
Issue number12
DOIs
Publication statusPublished - 16 Dec 1994

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