Formal synthesis of (+)-lactacystin from L-serine

Philip C. Bulman Page*, Ross L. Goodyear, Yohan Chan, Alexandra M. Z. Slawin, Steven M. Allin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


A formal, stereocontrolled synthesis of lactacystin has been completed from t-Bu-O-L-serine, providing the key intermediate 13, also useful for the generation of a range of C-9 analogues.

Original languageEnglish
Pages (from-to)30019-30032
Number of pages14
JournalRSC Advances
Issue number51
Early online date24 Sept 2019
Publication statusE-pub ahead of print - 24 Sept 2019


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