Fluorosugars: synthesis of the 2,3,4-trideoxy-2,3,4-trifluoro hexose analogues of D-glucose and D-altrose and assessment of their erythrocyte transmembrane transport

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Abstract

The 2,3,4-trideoxy-2,3,4-trifluoro hexose analogues of D-glucose and D-altrose were prepared and characterised and these novel sugar analogues were explored by 2D-F-19-EXSY NMR for their potential to cross erythrocyte (red blood cell) membranes, by comparison with the well known capacity of erythrocytes to transport D-glucose.

Original languageEnglish
Pages (from-to)5434-5436
Number of pages3
JournalChemical Communications
Volume46
Issue number30
DOIs
Publication statusPublished - 2010

Keywords

  • SUGARS
  • ALCOHOL
  • PROBES

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