Abstract
Genome sequencing identified a fluorinase gene in the marine bacterium Streptomyces xinghaiensis NRRL B-24674. Fermentation of the organism with inorganic fluoride (2 mM) demonstrated that the organism could biosynthesise fluoroacetate and that fluoroacetate production is sea-salt dependent. This is the first fluoro-metabolite producing microorganism identified from the marine environment.
| Original language | English |
|---|---|
| Pages (from-to) | 4828-4831 |
| Number of pages | 4 |
| Journal | Organic & Biomolecular Chemistry |
| Volume | 12 |
| Issue number | 27 |
| DOIs | |
| Publication status | Published - 2014 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 14 Life Below Water
Keywords
- FLUOROMETABOLITE BIOSYNTHESIS
- GENOME SEQUENCE
- CATTLEYA
- FLUORINASE
- IDENTIFICATION
- ENZYME
- 4-FLUOROTHREONINE
- SPECIFICITY
- SEDIMENT
Fingerprint
Dive into the research topics of 'Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674'. Together they form a unique fingerprint.Projects
- 1 Finished
-
Extending fluorinase C-18F-bond: Extending fluorinase [C-18F]-bond biocatalysis for Positron Emission Tomography (PET)
O'Hagan, D. (PI)
1/11/11 → 31/10/14
Project: Standard
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