Fluoroacetate biosynthesis from the marine-derived bacterium Streptomyces xinghaiensis NRRL B-24674

Sheng Huang, Long Ma, Ming Him Tong, Yi Yu*, David O'Hagan, Hai Deng

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

38 Citations (Scopus)

Abstract

Genome sequencing identified a fluorinase gene in the marine bacterium Streptomyces xinghaiensis NRRL B-24674. Fermentation of the organism with inorganic fluoride (2 mM) demonstrated that the organism could biosynthesise fluoroacetate and that fluoroacetate production is sea-salt dependent. This is the first fluoro-metabolite producing microorganism identified from the marine environment.

Original languageEnglish
Pages (from-to)4828-4831
Number of pages4
JournalOrganic & Biomolecular Chemistry
Volume12
Issue number27
DOIs
Publication statusPublished - 2014

Keywords

  • FLUOROMETABOLITE BIOSYNTHESIS
  • GENOME SEQUENCE
  • CATTLEYA
  • FLUORINASE
  • IDENTIFICATION
  • ENZYME
  • 4-FLUOROTHREONINE
  • SPECIFICITY
  • SEDIMENT

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