Projects per year
The synthesis of substituted all-cis-1,2,3-trifluorocylopropanes are described for the first time. The three fluorines located on each of the cyclopropyl carbons with a stereochemistry where they are all on the same face of the cyclopropane, imparts a significant polarity to the molecule, and the inherent conformational rigidity and lowering of Log P makes this motif attractive for exploration as a substituent for pharmaceuticals and agrochemicals research.
FingerprintDive into the research topics of 'Fluorine containing cyclopropanes: synthesis of aryl substituted all-cis 1,2,3-trifluorocylopropanes, a facially polar motif'. Together they form a unique fingerprint.
- 1 Finished
Partially fluorinated alkyl motifs: Partially fluorinated alkyl motifs for pharmaceuticals and agrochemicals research
7/04/18 → 15/07/21
Fluorine containing cyclopropanes: synthesis of aryl substituted all-cis 1,2,3-trifluorocylopropanes, a facially polar motif (dataset)
Cordes, D. B. (Creator), Cambridge Crystallographic Data Centre, 2019