Projects per year
Abstract
The fluorinase enzyme from S. cattleya is applied as a catalyst for the efficient incorporation of [F-18]-fluoride into [F-18]-5'-fluoro-5'-deoxyadenosine, [F-18]-5'-fluoro-5'-deoxyinosine and [F-18]-5-fluoro-5-deoxyribose for positron emission tomography (PET) applications.
Original language | English |
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Pages (from-to) | 652-654 |
Number of pages | 3 |
Journal | Chemical Communications |
Issue number | 6 |
DOIs | |
Publication status | Published - 14 Feb 2006 |
Keywords
- STREPTOMYCES-CATTLEYA
- BIOSYNTHESIS
- MECHANISM
- ACID
Fingerprint
Dive into the research topics of 'Fluorinase mediated C-F-18 bond formation, an enzymatic tool for PET labelling'. Together they form a unique fingerprint.Projects
- 2 Finished
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GR/S97491/01: Extending the substratespecificity of enzymatic fluorination. An entirely novel biocatalysis
O'Hagan, D. (PI)
1/10/04 → 30/09/07
Project: Standard
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BBS/B/04579: Structural, mechanistic and genetic studies of a fluorination enzyme and fluorometabolite pathway in Streptomyces cattleya
O'Hagan, D. (PI) & Naismith, J. (CoI)
1/02/04 → 31/10/08
Project: Standard