Five-membered rings with two nonadjacent heteroatoms with at least one other element

R Alan Aitken, Fiona Marie Fotherby

Research output: Chapter in Book/Report/Conference proceedingChapter


Developments in the chemistry of five-membered ring heterocycles containing two nonadjacent heteroatoms, with at least one silicon or germanium, in the period 2008–2020 are reviewed. Application of theoretical and structural methods to these compounds is described including X-ray structure determination and 29Si NMR. The major reactions of azasiloline and oxasiloline systems as well as heavier chalcogen and benzo analogues and disilole systems are discussed. This is followed by a briefer discussion of azagermoline, phosphagermoline and oxagermoline reactivity. Methods for the synthesis of both silicon and germanium systems are systematically covered. The systems containing germanium have mainly been reported recently and were hardly included in previous editions of Comprehensive Heterocyclic Chemistry.
Original languageEnglish
Title of host publicationComprehensive heterocyclic chemistry IV - a review of the literature 2008-2021
Subtitle of host publicationVolume 4: Five-membered rings with two heteroatoms, and their fused carbocyclic derivatives
EditorsR. A. Aitken
Place of PublicationAmsterdam
PublisherElsevier (incl. Pergamon )
Number of pages13
ISBN (Electronic)9780128186565
ISBN (Print)9780323912679, 9780128186558
Publication statusPublished - 23 Nov 2021


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