FIRST SYNTHESIS OF [1,3,5-C-13(3)]GALLIC ACID

Laura J. Marshall, Karl M. Cable, Nigel P. Botting

Research output: Contribution to journalArticlepeer-review

Abstract

Gallic acid is a phenolic plant metabolite which is normally encountered in plant tissues in ester form. These esters include a group of catechins with antioxidant properties which are found in green tea. Epigallocatechin-3-gallate is the most abundant catechin in green tea and has been shown to inhibit carcinogenesis.(1,2) An efficient and high-yielding synthesis for [1,3,5-C-13(3)]gallic acid from non-aromatic precursors is presented. This will allow compounds such as gallic acid and its derivatives to be used as internal standards for analysis by LC-MS or GC-MS techniques.

Original languageEnglish
Pages (from-to)456-457
Number of pages2
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Volume53
Issue number5-6
Publication statusPublished - 15 May 2010

Keywords

  • polyphenol
  • gallic acid
  • pyranone
  • antioxidants

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