Fatty acid-depleted albumin induces the formation of echovirus A particles

T Ward; RM Powell; Y Chaudhry; J Meredith; JW Almond; W Kraus; B Nelsen-Salz; HJ Eggers; DJ Evans

Fatty acid-depleted albumin induces the formation of echovirus A particles

T Ward, RM Powell, Y Chaudhry, J Meredith, JW Almond, W Kraus, B Nelsen-Salz, HJ Eggers, DJ Evans^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

Picornavirus infection requires virus uncoating, associated with the production of 135S "A" particles and 80S empty particles from 160S mature virions, to release the RNA genome into the cell cytoplasm. Normal albumin inhibits this process. We now show that when depleted of fatty acids, albumin induces the formation of echovirus A particles.

Original language	English
Pages (from-to)	3410-3412
Number of pages	3
Journal	Journal of Virology
Volume	74
Issue number	7
Publication status	Published - Apr 2000

Keywords

ACCELERATING FACTOR CD55
SOLUBLE CELL RECEPTORS
BOVINE ENTEROVIRUS
INHIBITION
RHODANINE

Cite this

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title = "Fatty acid-depleted albumin induces the formation of echovirus A particles",

abstract = "Picornavirus infection requires virus uncoating, associated with the production of 135S {"}A{"} particles and 80S empty particles from 160S mature virions, to release the RNA genome into the cell cytoplasm. Normal albumin inhibits this process. We now show that when depleted of fatty acids, albumin induces the formation of echovirus A particles.",

keywords = "ACCELERATING FACTOR CD55, SOLUBLE CELL RECEPTORS, BOVINE ENTEROVIRUS, INHIBITION, RHODANINE",

author = "T Ward and RM Powell and Y Chaudhry and J Meredith and JW Almond and W Kraus and B Nelsen-Salz and HJ Eggers and DJ Evans",

year = "2000",

month = apr,

language = "English",

volume = "74",

pages = "3410--3412",

journal = "Journal of Virology",

issn = "0022-538X",

publisher = "American Society for Microbiology",

number = "7",

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TY - JOUR

T1 - Fatty acid-depleted albumin induces the formation of echovirus A particles

AU - Ward, T

AU - Powell, RM

AU - Chaudhry, Y

AU - Meredith, J

AU - Almond, JW

AU - Kraus, W

AU - Nelsen-Salz, B

AU - Eggers, HJ

AU - Evans, DJ

PY - 2000/4

Y1 - 2000/4

N2 - Picornavirus infection requires virus uncoating, associated with the production of 135S "A" particles and 80S empty particles from 160S mature virions, to release the RNA genome into the cell cytoplasm. Normal albumin inhibits this process. We now show that when depleted of fatty acids, albumin induces the formation of echovirus A particles.

AB - Picornavirus infection requires virus uncoating, associated with the production of 135S "A" particles and 80S empty particles from 160S mature virions, to release the RNA genome into the cell cytoplasm. Normal albumin inhibits this process. We now show that when depleted of fatty acids, albumin induces the formation of echovirus A particles.

KW - ACCELERATING FACTOR CD55

KW - SOLUBLE CELL RECEPTORS

KW - BOVINE ENTEROVIRUS

KW - INHIBITION

KW - RHODANINE

M3 - Article

SN - 0022-538X

VL - 74

SP - 3410

EP - 3412

JO - Journal of Virology

JF - Journal of Virology

IS - 7

ER -

Fatty acid-depleted albumin induces the formation of echovirus A particles

Abstract

Keywords

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