Facile one-pot synthesis of 5-substituted hydantoins

Ross G. Murray, David M. Whitehead, Franck Le Strat, Stuart J. Conway

Research output: Contribution to journalArticlepeer-review

42 Citations (Scopus)

Abstract

5-Substituted and 5,5-disubstituted hydantoins are synthesised from the corresponding aldehydes or ketones, using a one-pot, gallium(III) triflate-catalysed procedure that is compatible with a range of substrates and solvents.

Original languageEnglish
Pages (from-to)988-991
Number of pages4
JournalOrganic & Biomolecular Chemistry
Volume6
DOIs
Publication statusPublished - 2008

Keywords

  • BUCHERER-BERGS REACTION
  • 5,5'-DISUBSTITUTED HYDANTOINS
  • ALPHA-AMINONITRILES
  • AGELAS-MAURITIANA
  • BINDING-SITE
  • RECEPTOR
  • STRECKER
  • LIGANDS
  • EFFICIENT
  • SPIROIMINODIHYDANTOIN

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