Exploring ICP-MS as a versatile technique: from imaging to chemical speciation analysis

Renata Stábile Amais, Aline Martins de Andrade, Ana Beatriz Santos da Silva, Daniel Carneiro Freitas, Danielle da Silva Francischini, Alan J. Stewart, Marco Aurelio Zezzi Arruda

Research output: Chapter in Book/Report/Conference proceedingChapter


Elements plays important role in healthy, became key pieces of information in medicine and life science. In this sense, this chapter reviews the most recent advances in inductively coupled plasma mass spectrometry and its hyphenation with some techniques focusing on a diversity of applications. Here, we are exploring the state-of-the-art regarding ICP-MS platforms from elemental imaging to chemical speciation analysis, putting in evidence some applications as laser ablation in the imaging mode, single particle, and chemical speciation in studies involving cancer and neurodegenerative diseases, biomarkers, among others. We also examine current trends in this field, focusing on the further development of ICP-MS-based approaches as well as analytical, biochemical, and medical aspects associated with the use of trace element analysis.
Original languageEnglish
Title of host publicationICP-MS and trace element analysis as tools for better understanding medical conditions
EditorsMarco Aurélio Zezzi Arruda, Jemmyson Romário de Jesus
Place of PublicationAmsterdam
Number of pages37
ISBN (Electronic)9780444643476
Publication statusPublished - 24 May 2022

Publication series

NameComprehensive analytical chemistry
ISSN (Print)0166-526X


  • Trace elements
  • Medical conditions
  • Healthy
  • Diseases
  • Biomarkers
  • Biological samples
  • Sample preparation
  • Nanoparticles
  • Elemental imaging
  • Hyphenated techniques


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