Experimental models of cryptococcosis

Wilber Sabiiti; Robin C May; E Rhiannon Pursall

doi:10.1155/2012/626745

Experimental models of cryptococcosis

Wilber Sabiiti
, Robin C May
, E Rhiannon Pursall

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have been exploited to probe this host-pathogen interaction. Here we review the range of experimental models that are available for cryptococcosis research and compare the relative advantages and limitations of the different systems.

Original language	English
Article number	626745
Journal	International Journal of Microbiology
Volume	2012
DOIs	https://doi.org/10.1155/2012/626745
Publication status	Published - 2012

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10.1155/2012/626745Licence: CC BY

Sabiiti2012InJnlMicrobiology_Cryptococcosis_CC
Copyright © 2012 Wilber Sabiiti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Final published version, 1.32 MBLicence: CC BY

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AB - Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have been exploited to probe this host-pathogen interaction. Here we review the range of experimental models that are available for cryptococcosis research and compare the relative advantages and limitations of the different systems.

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Experimental models of cryptococcosis

Abstract

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