Experimental models of cryptococcosis

Wilber Sabiiti, Robin C May, E Rhiannon Pursall

Research output: Contribution to journalReview articlepeer-review

23 Citations (Scopus)

Abstract

Cryptococcosis is a life-threatening fungal disease that infects around one million people each year. Establishment and progression of disease involves a complex interplay between the fungus and a diverse range of host cell types. Over recent years, numerous cellular, tissue, and animal models have been exploited to probe this host-pathogen interaction. Here we review the range of experimental models that are available for cryptococcosis research and compare the relative advantages and limitations of the different systems.
Original languageEnglish
Article number626745
JournalInternational Journal of Microbiology
Volume2012
DOIs
Publication statusPublished - 2012

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