Evolutionary history of the Coccolithoviridae

MJ Allen, DC Schroeder, MTG Holden, WH Wilson*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

55 Citations (Scopus)

Abstract

We recently determined the genome sequence of the Coccolithoviridae strain Emiliania huxleyi virus 86 (EhV-86), a giant double-stranded DNA (dsDNA) algal virus from the family Phycodnaviridae that infects the marine coccolithophorid E. huxleyi. Here, we determine the phylogenetic relationship between EhV-86 and other large dsDNA viruses. Twenty-five core genes common to nuclear-cytoplasmic large dsDNA virus genomes were identified in the EhV-86 genome; sequence from eight of these genes were used to create a phylogenetic tree in which EhV-86 was placed firmly with the two other members of the Phycodnaviridae. We have also identified a 100-kb region of the EhV-86 genome which appears to have transferred into this genome from an unknown source. Furthermore, the presence of six RNA polymerase subunits (unique among the Phycodnaviridae) suggests both a unique evolutionary history and a unique lifestyle for this intriguing virus.

Original languageEnglish
Pages (from-to)86-92
Number of pages7
JournalMolecular Biology and Evolution
Volume23
Issue number1
DOIs
Publication statusPublished - Jan 2006

Keywords

  • Phycodnaviridae
  • Coccolithoviridae
  • virus
  • evolution
  • NCLDV
  • Emiliania huxleyi
  • COMPLETE DNA-SEQUENCE
  • RANAVIRUS FAMILY IRIDOVIRIDAE
  • COMPLETE GENOMIC SEQUENCE
  • TUMORIGENIC POXVIRUS
  • EMILIANIA-HUXLEYI
  • VIRUS
  • ENTOMOPOXVIRUS
  • HOSTS

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