Evidence for the intrarenal renin-angiotensin system in the European lesser-spotted dogfish

A Wells; WG Anderson; Neil Hazon

doi:10.1046/j.1095-8649.2003.00234.x

Evidence for the intrarenal renin-angiotensin system in the European lesser-spotted dogfish

A Wells, WG Anderson, Neil Hazon

Research output: Contribution to journal › Article › peer-review

Abstract

The existence of an intrarenal renin-angiotensin system (RAS) in a perfused European lesser-spotted dogfish Scyliorhinus canicula trunk preparation was examined by the inhibition of angiotensin-converting enzyme by captopril. This resulted in a glomerular diuresis, an increase in urea and chloride clearance and excretion, and an increase in transport maxima for glucose. It is proposed that these results suggest the presence of an intrarenal RAS. (C) 2003 The Fisheries Society of the British Isles.

Original language	English
Pages (from-to)	1337 -1440
Number of pages	4
Journal	Journal of Fish Biology
Volume	63
DOIs	https://doi.org/10.1046/j.1095-8649.2003.00234.x
Publication status	Published - Nov 2003

Keywords

captopril
elasmobranch
intrarenal RAS
Scyliorhinus canicula
CONVERTING ENZYME
ARGININE VASOTOCIN
KIDNEY
VESSELS
TROUT

Access to Document

10.1046/j.1095-8649.2003.00234.x

Cite this

@article{9568eddcd9614db9ad4517de11b659c1,

title = "Evidence for the intrarenal renin-angiotensin system in the European lesser-spotted dogfish",

abstract = "The existence of an intrarenal renin-angiotensin system (RAS) in a perfused European lesser-spotted dogfish Scyliorhinus canicula trunk preparation was examined by the inhibition of angiotensin-converting enzyme by captopril. This resulted in a glomerular diuresis, an increase in urea and chloride clearance and excretion, and an increase in transport maxima for glucose. It is proposed that these results suggest the presence of an intrarenal RAS. (C) 2003 The Fisheries Society of the British Isles.",

keywords = "captopril, elasmobranch, intrarenal RAS, Scyliorhinus canicula, CONVERTING ENZYME, ARGININE VASOTOCIN, KIDNEY, VESSELS, TROUT",

author = "A Wells and WG Anderson and Neil Hazon",

year = "2003",

month = nov,

doi = "10.1046/j.1095-8649.2003.00234.x",

language = "English",

volume = "63",

pages = "1337 --1440",

journal = "Journal of Fish Biology",

issn = "0022-1112",

publisher = "John Wiley & Sons, Ltd",

}

TY - JOUR

T1 - Evidence for the intrarenal renin-angiotensin system in the European lesser-spotted dogfish

AU - Wells, A

AU - Anderson, WG

AU - Hazon, Neil

PY - 2003/11

Y1 - 2003/11

N2 - The existence of an intrarenal renin-angiotensin system (RAS) in a perfused European lesser-spotted dogfish Scyliorhinus canicula trunk preparation was examined by the inhibition of angiotensin-converting enzyme by captopril. This resulted in a glomerular diuresis, an increase in urea and chloride clearance and excretion, and an increase in transport maxima for glucose. It is proposed that these results suggest the presence of an intrarenal RAS. (C) 2003 The Fisheries Society of the British Isles.

AB - The existence of an intrarenal renin-angiotensin system (RAS) in a perfused European lesser-spotted dogfish Scyliorhinus canicula trunk preparation was examined by the inhibition of angiotensin-converting enzyme by captopril. This resulted in a glomerular diuresis, an increase in urea and chloride clearance and excretion, and an increase in transport maxima for glucose. It is proposed that these results suggest the presence of an intrarenal RAS. (C) 2003 The Fisheries Society of the British Isles.

KW - captopril

KW - elasmobranch

KW - intrarenal RAS

KW - Scyliorhinus canicula

KW - CONVERTING ENZYME

KW - ARGININE VASOTOCIN

KW - KIDNEY

KW - VESSELS

KW - TROUT

UR - http://www.scopus.com/inward/record.url?scp=2342514175&partnerID=8YFLogxK

U2 - 10.1046/j.1095-8649.2003.00234.x

DO - 10.1046/j.1095-8649.2003.00234.x

M3 - Article

SN - 0022-1112

VL - 63

SP - 1337

EP - 1440

JO - Journal of Fish Biology

JF - Journal of Fish Biology

ER -

Evidence for the intrarenal renin-angiotensin system in the European lesser-spotted dogfish

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this