Evaluation of (2S,4S)/(2R,4R) and (2S,4R)/(2R,4S) 6,6-N,N-dimethyl-2-methyl-2-oxo-1,3-dioxa-4-hexadecyl-6,aza-2-phosphacyc looctane bromide as inhibitors for protein kinase C, carnitine octanoyltransferase, and carnitine palmitoyltransferase

G. Kumaravel*, N. Nic a' Bháird, F. R. Fronczek, R. R. Ramsay, C. L. Ashendel, R. D. Gandour

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

(2S,4S)/(2R,4R) and (2S,4R)/(2R,4S) 6,6-N,N-dimethyl-2-methyl-2-oxo-1,3-dioxa-4-hexadecyl-6-aza-2-phosphacyc looctane bromide strongly inhibited protein kinase C and moderately inhibited carnitine octanoyltransferase and carnitine palmitoyltransferase.

Original languageEnglish
Pages (from-to)883-886
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume4
Issue number7
DOIs
Publication statusPublished - 1 Jan 1994

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