Ethyl 4-((2-hydroxyethyl)amino)-2-(4-methoxyphenyl)-1-methyl-5-oxo-2,5-di­ hydro-1H-pyrrole-3-carboxylat

Fatin Nur Ain Abdul  Rashid; Mohd Fazli Mohammat; Mohd Abdul Fatah Abdul  Manan; Ayisy Amirul Afti Bakhtiar  Afendy; David Bradford Cordes; Aidan McKay

doi:10.1107/S2414314624012227

Ethyl 4-((2-hydroxyethyl)amino)-2-(4-methoxyphenyl)-1-methyl-5-oxo-2,5-di hydro-1H-pyrrole-3-carboxylat

Fatin Nur Ain Abdul Rashid, Mohd Fazli Mohammat, Mohd Abdul Fatah Abdul Manan, Ayisy Amirul Afti Bakhtiar Afendy, David Bradford Cordes, Aidan McKay

Research output: Contribution to journal › Article › peer-review

Abstract

In the title compound, C17H22N2O5 the pyrrolidine ring is almost planar and subtends a dihedral angle of 85.77 (7)° with the pendant phenyl ring. An intramolecular N—H⋯O hydrogen bond generates an S(6) loop. In the crystal, the compound forms inversion dimers through O—H⋯O hydrogen bonds from the disordered hydroxyl group to either the hydroxyl or ester carbonyl O atom of the adjacent molecule.

Original language	English
Article number	x241222
Number of pages	9
Journal	IUCrData
Volume	9
Issue number	12
DOIs	https://doi.org/10.1107/S2414314624012227
Publication status	Published - 20 Dec 2024

Keywords

crystal structure
oxopyrrolidine
racemic
hydrogen bond

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10.1107/S2414314624012227Licence: CC BY

Rashid_2024_IUCrData_Ethyl-4_CCBY
Copyright © 2024 the Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution (CC-BY) Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. The final published version was originally available at https://doi.org/10.1107/S2414314624012227
Final published version, 2.18 MBLicence: CC BY

CCDC 2411088: Experimental Crystal Structure Determination
Rashid, F. N. A. A. (Creator), Mohammat, M. F. (Creator), Manan, M. A. F. A. (Creator), Afendy, A. A. A. B. (Creator), Cordes, D. B. (Creator) & McKay, A. P. (Creator), Cambridge Crystallographic Data Centre, 2024
DOI: 10.5517/ccdc.csd.cc2lxy1j
Dataset

Cite this

@article{e997e29038bc448d8a5a2009e298549d,

title = "Ethyl 4-((2-hydroxyethyl)amino)-2-(4-methoxyphenyl)-1-methyl-5-oxo-2,5-di hydro-1H-pyrrole-3-carboxylat",

abstract = "In the title compound, C17H22N2O5 the pyrrolidine ring is almost planar and subtends a dihedral angle of 85.77 (7)° with the pendant phenyl ring. An intramolecular N—H⋯O hydrogen bond generates an S(6) loop. In the crystal, the compound forms inversion dimers through O—H⋯O hydrogen bonds from the disordered hydroxyl group to either the hydroxyl or ester carbonyl O atom of the adjacent molecule.",

keywords = "crystal structure, oxopyrrolidine, racemic, hydrogen bond",

author = "Rashid, {Fatin Nur Ain Abdul} and Mohammat, {Mohd Fazli} and Manan, {Mohd Abdul Fatah Abdul} and Afendy, {Ayisy Amirul Afti Bakhtiar} and Cordes, {David Bradford} and Aidan McKay",

note = "Funding: The authors acknowledge Universiti Teknologi MARA for financial support and the Centre of Chemical Synthesis & Polymer Technology (CCSPT), Institute of Science, Universiti Teknologi MARA Puncak Alam, Selangor, Malaysia for the provision of laboratory facilities.",

year = "2024",

month = dec,

day = "20",

doi = "10.1107/S2414314624012227",

language = "English",

volume = "9",

journal = "IUCrData",

issn = "2414-3146",

publisher = "International Union of Crystallography",

number = "12",

}

TY - JOUR

T1 - Ethyl 4-((2-hydroxyethyl)amino)-2-(4-methoxyphenyl)-1-methyl-5-oxo-2,5-di hydro-1H-pyrrole-3-carboxylat

AU - Rashid, Fatin Nur Ain Abdul

AU - Mohammat, Mohd Fazli

AU - Manan, Mohd Abdul Fatah Abdul

AU - Afendy, Ayisy Amirul Afti Bakhtiar

AU - Cordes, David Bradford

AU - McKay, Aidan

N1 - Funding: The authors acknowledge Universiti Teknologi MARA for financial support and the Centre of Chemical Synthesis & Polymer Technology (CCSPT), Institute of Science, Universiti Teknologi MARA Puncak Alam, Selangor, Malaysia for the provision of laboratory facilities.

PY - 2024/12/20

Y1 - 2024/12/20

N2 - In the title compound, C17H22N2O5 the pyrrolidine ring is almost planar and subtends a dihedral angle of 85.77 (7)° with the pendant phenyl ring. An intramolecular N—H⋯O hydrogen bond generates an S(6) loop. In the crystal, the compound forms inversion dimers through O—H⋯O hydrogen bonds from the disordered hydroxyl group to either the hydroxyl or ester carbonyl O atom of the adjacent molecule.

AB - In the title compound, C17H22N2O5 the pyrrolidine ring is almost planar and subtends a dihedral angle of 85.77 (7)° with the pendant phenyl ring. An intramolecular N—H⋯O hydrogen bond generates an S(6) loop. In the crystal, the compound forms inversion dimers through O—H⋯O hydrogen bonds from the disordered hydroxyl group to either the hydroxyl or ester carbonyl O atom of the adjacent molecule.

KW - crystal structure

KW - oxopyrrolidine

KW - racemic

KW - hydrogen bond

U2 - 10.1107/S2414314624012227

DO - 10.1107/S2414314624012227

M3 - Article

SN - 2414-3146

VL - 9

JO - IUCrData

JF - IUCrData

IS - 12

M1 - x241222

ER -

Ethyl 4-((2-hydroxyethyl)amino)-2-(4-methoxyphenyl)-1-methyl-5-oxo-2,5-di­ hydro-1H-pyrrole-3-carboxylat

Abstract

Keywords

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Datasets

CCDC 2411088: Experimental Crystal Structure Determination

Cite this

Ethyl 4-((2-hydroxyethyl)amino)-2-(4-methoxyphenyl)-1-methyl-5-oxo-2,5-di hydro-1H-pyrrole-3-carboxylat