Enhanced accuracy in novel mirror drawing after repetitive transcranial magnetic stimulation-induced proprioceptive deafferentation

D Balslev*, LOD Christensen, JH Lee, I Law, OB Paulson, RC Miall

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

50 Citations (Scopus)

Abstract

When performing visually guided actions under conditions of perturbed visual feedback, e. g., in a mirror or a video camera, there is a spatial conflict between visual and proprioceptive information. Recent studies have shown that subjects without proprioception avoid this conflict and show a performance benefit. In this study, we tested whether deafferentation induced by repetitive transcranial magnetic stimulation (rTMS) can improve mirror tracing skills in normal subjects. Hand trajectory error during novel mirror drawing was compared across two groups of subjects that received either 1 Hz rTMS over the somatosensory cortex contralateral to the hand or sham stimulation. Mirror tracing was more accurate after rTMS than after sham stimulation. Using a position-matching task, we confirmed that rTMS reduced proprioceptive acuity and that this reduction was largest when the coil was placed at an anterior parietal site. It is thus possible, with rTMS, to enhance motor performance in tasks involving a visuoproprioceptive conflict, presumably by reducing the excitability of somatosensory cortical areas that contribute to the sense of hand position.

Original languageEnglish
Pages (from-to)9698-9702
Number of pages5
JournalThe Journal of Neuroscience
Volume24
Issue number43
DOIs
Publication statusPublished - 27 Oct 2004

Keywords

  • proprioceptive
  • visual
  • somatosensory
  • hand
  • parietal
  • motor activity
  • FIBER SENSORY NEUROPATHY
  • PRIMARY MOTOR CORTEX
  • POSITION SENSE
  • SOMATOSENSORY CORTEX
  • POSTCENTRAL-GYRUS
  • PARIETAL-LOBE
  • EXCITABILITY
  • PERCEPTION
  • HAND
  • REPRESENTATIONS

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