Engineering thermostability - lessons from thermophilic proteins

R J M RUSSELL, G L TAYLOR

Research output: Contribution to journalArticlepeer-review

103 Citations (Scopus)

Abstract

As several groups begin to tap the rich pickings found in the Archaea-a vast kingdom that stretches the concept of life as we know it-the structures of proteins from hyperthermophiles are being elucidated. Certain features are beginning to emerge, such as compactness and hydrophobic clustering, but the ability to engineer these features into temperature-intolerant proteins is still some way off.

Original languageEnglish
Pages (from-to)370-374
Number of pages5
JournalCurrent Opinion in Biotechnology
Volume6
Issue number4
Publication statusPublished - Aug 1995

Keywords

  • STABILITY
  • DEHYDROGENASE
  • ARCHAEA

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