TY - JOUR
T1 - Elevated levels of mixed-hand preference in dyslexia
T2 - meta-analyses of 68 studies
AU - Packheiser, Julian
AU - Papadatou-Pastou, Marietta
AU - Koufaki, Angeliki
AU - Paracchini, Silvia
AU - Stein, Clara C
AU - Schmitz, Judith
AU - Ocklenburg, Sebastian
N1 - Funding: Julian Packheiser was supported by the German National Academy of Sciences Leopoldina (LDPS 2021-05).
PY - 2023/11
Y1 - 2023/11
N2 - Since almost a hundred years, psychologists have investigated the link between hand preference and dyslexia. We present a meta-analysis to determine whether there is indeed an increase in atypical hand preference in dyslexia. We included studies used in two previous meta-analyses (Bishop, 1990; Eglinton & Annett, 1994) as well as studies identified through PubMed MEDLINE, PsycInfo, Google Scholar, and Web of Science up to August 2022. K = 68 studies (n = 4660 individuals with dyslexia; n = 40845 controls) were entered into three random effects meta-analyses using the odds ratio as the effect size (non-right-handers; left-handers; mixed-handers vs. total). Evidence of elevated levels of atypical hand preference in dyslexia emerged that were especially pronounced for mixed-hand preference (OR = 1.57), although this category was underdefined. Differences in (direction or degree) of hand skill or degree of hand preference could not be assessed as no pertinent studies were located. Our findings allow for robust conclusions only for a relationship of mixed-hand preference with dyslexia.
AB - Since almost a hundred years, psychologists have investigated the link between hand preference and dyslexia. We present a meta-analysis to determine whether there is indeed an increase in atypical hand preference in dyslexia. We included studies used in two previous meta-analyses (Bishop, 1990; Eglinton & Annett, 1994) as well as studies identified through PubMed MEDLINE, PsycInfo, Google Scholar, and Web of Science up to August 2022. K = 68 studies (n = 4660 individuals with dyslexia; n = 40845 controls) were entered into three random effects meta-analyses using the odds ratio as the effect size (non-right-handers; left-handers; mixed-handers vs. total). Evidence of elevated levels of atypical hand preference in dyslexia emerged that were especially pronounced for mixed-hand preference (OR = 1.57), although this category was underdefined. Differences in (direction or degree) of hand skill or degree of hand preference could not be assessed as no pertinent studies were located. Our findings allow for robust conclusions only for a relationship of mixed-hand preference with dyslexia.
KW - Handedness
KW - Dyslexia
KW - Laterality
KW - Hemispheric asymmetry
KW - Reading
UR - https://doi.org/10.31234/osf.io/rqdma
U2 - 10.1016/j.neubiorev.2023.105420
DO - 10.1016/j.neubiorev.2023.105420
M3 - Article
SN - 0149-7634
VL - 154
JO - Neuroscience and Biobehavioral Reviews
JF - Neuroscience and Biobehavioral Reviews
M1 - 105420
ER -