Efficient Sonogashira reactions of aryl bromides with alkynylsilanes catalyzed by a palladium/imidazolium salt system

C L  Yang; Steven Patrick Nolan

doi:10.1021/om011021k

Efficient Sonogashira reactions of aryl bromides with alkynylsilanes catalyzed by a palladium/imidazolium salt system

C L Yang, Steven Patrick Nolan

Research output: Contribution to journal › Article › peer-review

Abstract

A palladium/imidazolium chloride system has been used to mediate the cross-coupling reaction of aryl halides with alkynylsilanes. The combination of 3 mol % Pd(OAc)(2) and 6 mol % IMes.HCl in the presence of Cs2CO3 as base proves to be a highly efficient system in assisting coupling of aryl bromides with alkynylsilanes.

Original language	English
Pages (from-to)	1020-1022
Number of pages	3
Journal	Organometallics
Volume	21
Issue number	6
DOIs	https://doi.org/10.1021/om011021k
Publication status	Published - 18 Mar 2002

Keywords

CROSS-COUPLING REACTIONS
HETEROCYCLIC CARBENE COMPLEXES
OLEFIN METATHESIS CATALYSTS
ROOM-TEMPERATURE
METAL-COMPLEXES
CHLORIDE SYSTEM
PALLADIUM
RUTHENIUM
LIGANDS
AMINATION

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@article{49592f8a4dad4a77871d2c2bdb545716,

title = "Efficient Sonogashira reactions of aryl bromides with alkynylsilanes catalyzed by a palladium/imidazolium salt system",

abstract = "A palladium/imidazolium chloride system has been used to mediate the cross-coupling reaction of aryl halides with alkynylsilanes. The combination of 3 mol % Pd(OAc)(2) and 6 mol % IMes.HCl in the presence of Cs2CO3 as base proves to be a highly efficient system in assisting coupling of aryl bromides with alkynylsilanes.",

keywords = "CROSS-COUPLING REACTIONS, HETEROCYCLIC CARBENE COMPLEXES, OLEFIN METATHESIS CATALYSTS, ROOM-TEMPERATURE, METAL-COMPLEXES, CHLORIDE SYSTEM, PALLADIUM, RUTHENIUM, LIGANDS, AMINATION",

author = "Yang, {C L} and Nolan, {Steven Patrick}",

year = "2002",

month = mar,

day = "18",

doi = "10.1021/om011021k",

language = "English",

volume = "21",

pages = "1020--1022",

journal = "Organometallics",

issn = "0276-7333",

publisher = "American Chemical Society (ACS)",

number = "6",

}

TY - JOUR

T1 - Efficient Sonogashira reactions of aryl bromides with alkynylsilanes catalyzed by a palladium/imidazolium salt system

AU - Yang, C L

AU - Nolan, Steven Patrick

PY - 2002/3/18

Y1 - 2002/3/18

N2 - A palladium/imidazolium chloride system has been used to mediate the cross-coupling reaction of aryl halides with alkynylsilanes. The combination of 3 mol % Pd(OAc)(2) and 6 mol % IMes.HCl in the presence of Cs2CO3 as base proves to be a highly efficient system in assisting coupling of aryl bromides with alkynylsilanes.

AB - A palladium/imidazolium chloride system has been used to mediate the cross-coupling reaction of aryl halides with alkynylsilanes. The combination of 3 mol % Pd(OAc)(2) and 6 mol % IMes.HCl in the presence of Cs2CO3 as base proves to be a highly efficient system in assisting coupling of aryl bromides with alkynylsilanes.

KW - CROSS-COUPLING REACTIONS

KW - HETEROCYCLIC CARBENE COMPLEXES

KW - OLEFIN METATHESIS CATALYSTS

KW - ROOM-TEMPERATURE

KW - METAL-COMPLEXES

KW - CHLORIDE SYSTEM

KW - PALLADIUM

KW - RUTHENIUM

KW - LIGANDS

KW - AMINATION

U2 - 10.1021/om011021k

DO - 10.1021/om011021k

M3 - Article

SN - 0276-7333

VL - 21

SP - 1020

EP - 1022

JO - Organometallics

JF - Organometallics

IS - 6

ER -

Efficient Sonogashira reactions of aryl bromides with alkynylsilanes catalyzed by a palladium/imidazolium salt system

Abstract

Keywords

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