Projects per year
Abstract
The one-pot addition and cyclization of 1,5-diepoxyhexane with a range of organolithium species provides efficient access to 2,5-substituted tetrahydrofurans (THFs), common structural motifs found in a range of natural products and pharmaceutical ingredients, Extension of this reaction to triepoxides has also been demonstrated to access adjacently linked bis-THF motifs in a single step. (C) 2008 Elsevier Ltd. All rights reserved.
Original language | English |
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Pages (from-to) | 6784-6786 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 49 |
Issue number | 48 |
DOIs | |
Publication status | Published - 24 Nov 2008 |
Keywords
- KINETIC RESOLUTION
- TERMINAL EPOXIDES
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Dive into the research topics of 'Efficient access to 2,5-substituted tetrahydrofurans via a one-pot cyclization of di- and triepoxides'. Together they form a unique fingerprint.Projects
- 2 Finished
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Research Grants Scheme 2007/R1: Research Grants Scheme- 2007/R1
Florence, G. J. (PI)
1/08/07 → 31/07/08
Project: Standard
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The Royal Society 516002.K501/kk: Dr G Florence research fellowship application - 2005
Florence, G. J. (PI)
1/10/05 → 30/09/10
Project: Fellowship