Effect of Electronic Enrichment of NHCs on the Catalytic Activity of [Pd(NHC)(acac)Cl] in Buchwald−Hartwig Coupling

Gaetan Romain Le Duc, Sebastien Michel Bernard Meiries, Steven Patrick Nolan

Research output: Contribution to journalArticlepeer-review

55 Citations (Scopus)

Abstract

A series of [Pd(NHC)(acac)Cl] (NHC = Nheterocyclic carbene) complexes have been synthesized and characterized to investigate the electronic and steric effects of NHC ligands in catalysis. Their reactivity in Buchwald−Hartwig coupling has been explored and compared with that of their nonmethoxylated congeners. Combining the optimal steric and electronic properties, [Pd(IHeptOMe)(acac)Cl] performed excellently in the palladium-catalyzed amination of deactivated aryl chlorides with various anilines.
Original languageEnglish
Pages (from-to)7547-7551
Number of pages5
JournalOrganometallics
Volume32
Issue number24
Early online date19 Nov 2013
DOIs
Publication statusPublished - 23 Dec 2013

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