Does obesity influence clinical outcome at nine years following total knee replacement?

R A Collins, P J Walmsley, A K Amin, I J Brenkel, R A E Clayton

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61 Citations (Scopus)


A total of 445 consecutive primary total knee replacements (TKRs) were followed up prospectively at six and 18 months and three, six and nine years. Patients were divided into two groups: non-obese (body mass index (BMI) < 30 kg/m(2)) and obese (BMI ≥ 30 kg/m(2)). The obese group was subdivided into mildly obese (BMI 30 to 35 kg/m(2)) and highly obese (BMI ≥ 35 kg/m(2)) in order to determine the effects of increasing obesity on outcome. The clinical data analysed included the Knee Society score, peri-operative complications and implant survival. There was no difference in the overall complication rates or implant survival between the two groups. Obesity appears to have a small but significant adverse effect on clinical outcome, with highly obese patients showing lower function scores than non-obese patients. However, significant improvements in outcome are sustained in all groups nine years after TKR. Given the substantial, sustainable relief of symptoms after TKR and the low peri-operative complication and revision rates in these two groups, we have found no reason to limit access to TKR in obese patients.

Original languageEnglish
Pages (from-to)1351-5
Number of pages5
JournalJournal of Bone and Joint Surgery
Issue number10
Publication statusPublished - Oct 2012


  • Adult
  • Aged
  • Aged, 80 and over
  • Arthroplasty, Replacement, Knee
  • Body Mass Index
  • Female
  • Humans
  • Male
  • Middle Aged
  • Obesity
  • Osteoarthritis, Knee
  • Treatment Outcome


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