Abstract
The correct processing of Okazaki fragments during lagging-strand DNA replication has a vital role in maintaining genome integrity. Recent findings suggest that, in eukaryotes, the processing of Okazaki fragments occurs by a two-step mechanism governed by the single-stranded DNA binding factor RPA.
| Original language | English |
|---|---|
| Pages (from-to) | R842-R844 |
| Number of pages | 3 |
| Journal | Current Biology |
| Volume | 11 |
| Issue number | 20 |
| DOIs | |
| Publication status | Published - 16 Oct 2001 |
Keywords
- ESSENTIAL IN-VIVO
- ENDONUCLEASE ACTIVITY
- YEAST
- HELICASE
- NUCLEASE
- SUGGESTS
- ENCODES
- PROTEIN
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