DNA replication: Partners in the Okazaki two-step

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)

Abstract

The correct processing of Okazaki fragments during lagging-strand DNA replication has a vital role in maintaining genome integrity. Recent findings suggest that, in eukaryotes, the processing of Okazaki fragments occurs by a two-step mechanism governed by the single-stranded DNA binding factor RPA.

Original languageEnglish
Pages (from-to)R842-R844
Number of pages3
JournalCurrent Biology
Volume11
Issue number20
DOIs
Publication statusPublished - 16 Oct 2001

Keywords

  • ESSENTIAL IN-VIVO
  • ENDONUCLEASE ACTIVITY
  • YEAST
  • HELICASE
  • NUCLEASE
  • SUGGESTS
  • ENCODES
  • PROTEIN

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