DNA replication: Partners in the Okazaki two-step

Stuart Andrew MacNeill

doi:10.1016/S0960-9822(01)00500-0

DNA replication: Partners in the Okazaki two-step

Stuart Andrew MacNeill

Research output: Contribution to journal › Article › peer-review

48 Citations (Scopus)

Abstract

The correct processing of Okazaki fragments during lagging-strand DNA replication has a vital role in maintaining genome integrity. Recent findings suggest that, in eukaryotes, the processing of Okazaki fragments occurs by a two-step mechanism governed by the single-stranded DNA binding factor RPA.

Original language	English
Pages (from-to)	R842-R844
Number of pages	3
Journal	Current Biology
Volume	11
Issue number	20
DOIs	https://doi.org/10.1016/S0960-9822(01)00500-0
Publication status	Published - 16 Oct 2001

Keywords

ESSENTIAL IN-VIVO
ENDONUCLEASE ACTIVITY
YEAST
HELICASE
NUCLEASE
SUGGESTS
ENCODES
PROTEIN

Access to Document

10.1016/S0960-9822(01)00500-0

Cite this

@article{1abe5c7d86d74a06b3f5dd09ff932130,

title = "DNA replication: Partners in the Okazaki two-step",

abstract = "The correct processing of Okazaki fragments during lagging-strand DNA replication has a vital role in maintaining genome integrity. Recent findings suggest that, in eukaryotes, the processing of Okazaki fragments occurs by a two-step mechanism governed by the single-stranded DNA binding factor RPA.",

keywords = "ESSENTIAL IN-VIVO, ENDONUCLEASE ACTIVITY, YEAST, HELICASE, NUCLEASE, SUGGESTS, ENCODES, PROTEIN",

author = "MacNeill, {Stuart Andrew}",

year = "2001",

month = oct,

day = "16",

doi = "10.1016/S0960-9822(01)00500-0",

language = "English",

volume = "11",

pages = "R842--R844",

journal = "Current Biology",

issn = "0960-9822",

publisher = "Cell Press",

number = "20",

}

TY - JOUR

T1 - DNA replication: Partners in the Okazaki two-step

AU - MacNeill, Stuart Andrew

PY - 2001/10/16

Y1 - 2001/10/16

N2 - The correct processing of Okazaki fragments during lagging-strand DNA replication has a vital role in maintaining genome integrity. Recent findings suggest that, in eukaryotes, the processing of Okazaki fragments occurs by a two-step mechanism governed by the single-stranded DNA binding factor RPA.

AB - The correct processing of Okazaki fragments during lagging-strand DNA replication has a vital role in maintaining genome integrity. Recent findings suggest that, in eukaryotes, the processing of Okazaki fragments occurs by a two-step mechanism governed by the single-stranded DNA binding factor RPA.

KW - ESSENTIAL IN-VIVO

KW - ENDONUCLEASE ACTIVITY

KW - YEAST

KW - HELICASE

KW - NUCLEASE

KW - SUGGESTS

KW - ENCODES

KW - PROTEIN

U2 - 10.1016/S0960-9822(01)00500-0

DO - 10.1016/S0960-9822(01)00500-0

M3 - Article

SN - 0960-9822

VL - 11

SP - R842-R844

JO - Current Biology

JF - Current Biology

IS - 20

ER -

DNA replication: Partners in the Okazaki two-step

Abstract

Keywords

Access to Document

Fingerprint

Cite this