DNA Methylation in Stroke. Update of Latest Advances

Jerzy Krupinski, Caty Carrera, Elena Muiño, Nuria Torres, Raid Al-Baradie, Natalia Cullell, Israel Fernandez-Cadenas*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

18 Citations (Scopus)

Abstract

Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-coding RNAs. Epigenetic factors have mainly been associated with cancer but also with other diseases and conditions such as diabetes or obesity. In addition, epigenetic modifications could play an important role in cardiovascular diseases, including stroke. We review the latest advances in stroke epigenetics, focusing on DNA methylation studies and the future perspectives in this field.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalComputational and Structural Biotechnology Journal
Volume16
DOIs
Publication statusPublished - 2018

Keywords

  • Epigenetics
  • EWAs
  • Genetics
  • GWAs
  • Stroke

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