DNA Methylation in Stroke. Update of Latest Advances

Jerzy Krupinski; Caty Carrera; Elena Muiño; Nuria Torres; Raid Al-Baradie; Natalia Cullell; Israel Fernandez-Cadenas

doi:10.1016/j.csbj.2017.12.001

DNA Methylation in Stroke. Update of Latest Advances

Jerzy Krupinski, Caty Carrera, Elena Muiño, Nuria Torres, Raid Al-Baradie, Natalia Cullell, Israel Fernandez-Cadenas^*

^*Corresponding author for this work

School of Biology

Research output: Contribution to journal › Short survey › peer-review

Abstract

Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-coding RNAs. Epigenetic factors have mainly been associated with cancer but also with other diseases and conditions such as diabetes or obesity. In addition, epigenetic modifications could play an important role in cardiovascular diseases, including stroke. We review the latest advances in stroke epigenetics, focusing on DNA methylation studies and the future perspectives in this field.

Original language	English
Pages (from-to)	1-5
Number of pages	5
Journal	Computational and Structural Biotechnology Journal
Volume	16
DOIs	https://doi.org/10.1016/j.csbj.2017.12.001
Publication status	Published - 2018

Keywords

Epigenetics
EWAs
Genetics
GWAs
Stroke

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.csbj.2017.12.001

Cite this

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title = "DNA Methylation in Stroke. Update of Latest Advances",

abstract = "Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-coding RNAs. Epigenetic factors have mainly been associated with cancer but also with other diseases and conditions such as diabetes or obesity. In addition, epigenetic modifications could play an important role in cardiovascular diseases, including stroke. We review the latest advances in stroke epigenetics, focusing on DNA methylation studies and the future perspectives in this field.",

keywords = "Epigenetics, EWAs, Genetics, GWAs, Stroke",

author = "Jerzy Krupinski and Caty Carrera and Elena Mui{\~n}o and Nuria Torres and Raid Al-Baradie and Natalia Cullell and Israel Fernandez-Cadenas",

note = "Publisher Copyright: {\textcopyright} 2017 The Authors",

year = "2018",

doi = "10.1016/j.csbj.2017.12.001",

language = "English",

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T1 - DNA Methylation in Stroke. Update of Latest Advances

AU - Krupinski, Jerzy

AU - Carrera, Caty

AU - Muiño, Elena

AU - Torres, Nuria

AU - Al-Baradie, Raid

AU - Cullell, Natalia

AU - Fernandez-Cadenas, Israel

PY - 2018

Y1 - 2018

N2 - Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-coding RNAs. Epigenetic factors have mainly been associated with cancer but also with other diseases and conditions such as diabetes or obesity. In addition, epigenetic modifications could play an important role in cardiovascular diseases, including stroke. We review the latest advances in stroke epigenetics, focusing on DNA methylation studies and the future perspectives in this field.

AB - Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-coding RNAs. Epigenetic factors have mainly been associated with cancer but also with other diseases and conditions such as diabetes or obesity. In addition, epigenetic modifications could play an important role in cardiovascular diseases, including stroke. We review the latest advances in stroke epigenetics, focusing on DNA methylation studies and the future perspectives in this field.

KW - Epigenetics

KW - EWAs

KW - Genetics

KW - GWAs

KW - Stroke

UR - http://www.scopus.com/inward/record.url?scp=85039703348&partnerID=8YFLogxK

U2 - 10.1016/j.csbj.2017.12.001

DO - 10.1016/j.csbj.2017.12.001

M3 - Short survey

AN - SCOPUS:85039703348

SN - 2001-0370

VL - 16

SP - 1

EP - 5

JO - Computational and Structural Biotechnology Journal

JF - Computational and Structural Biotechnology Journal

ER -

DNA Methylation in Stroke. Update of Latest Advances

Abstract

Keywords

UN SDGs

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