Disparity-Tuned Population Responses from Human Visual Cortex

Benoit R. Cottereau*, Suzanne P. Mckee, Justin Michael Ales, Anthony M. Norcia

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

55 Citations (Scopus)

Abstract

We used source imaging of visual evoked potentials to measure neural population responses over a wide range of horizontal disparities (0.5-64 arcmin). The stimulus was a central disk that moved back and forth across the fixation plane at 2 Hz, surrounded either by binocularly uncorrelated dots (disparity noise) or by correlated dots presented in the fixation plane. Both disk and surround were composed of dynamic random dots to remove coherent monocular information. Disparity tuning was measured in five visual regions of interest (ROIs) [V1, human middle temporal area (hMT+), V4, lateral occipital complex (LOC), and V3A], defined in separate functional magnetic resonance imaging scans. The disparity tuning functions peaked between 2 and 16 arcmin for both types of surround in each ROI. Disparity tuning in the V1 ROI was unaffected by the type of surround, but surround correlation altered both the amplitude and phase of the disparity responses in the other ROIs. Response amplitude increased when the disk was in front of the surround in the V3A and LOC ROIs, indicating that these areas encode figure-ground relationships and object convexity. The correlated surround produced a consistent phase lag at the second harmonic in the hMT+ and V4 ROIs without a change in amplitude, while in the V3A ROI, both phase and amplitude effects were observed. Sensitivity to disparity context is thus widespread in visual cortex, but the dynamics of these contextual interactions differ across regions.

Original languageEnglish
Pages (from-to)954-965
Number of pages12
JournalThe Journal of Neuroscience
Volume31
Issue number3
DOIs
Publication statusPublished - 19 Jan 2011

Keywords

  • VENTRAL OCCIPITAL CORTEX
  • RANDOM-DOT STEREOGRAMS
  • HUMAN BRAIN
  • AREA V4
  • STEREOSCOPIC DEPTH
  • RELATIVE DISPARITY
  • HORIZONTAL DISPARITY
  • CORTICAL ACTIVITY
  • V1 NEURONS
  • MACAQUE

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