Deep tissue contractility sensing with biointegrated microlasers

Marcel Schubert; Lewis Woolfson; Isla R.M. Barnard; Amy M. Dorward; Becky Casement; Soraya Caixeiro; Andrew Morton; Gavin B. Robertson; Paul L. Appleton; Gareth B. Miles; Carl S. Tucker; Samantha J. Pitt; Malte C. Gather

Deep tissue contractility sensing with biointegrated microlasers

Marcel Schubert^*
, Lewis Woolfson
, Isla R.M. Barnard
, Amy M. Dorward
, Becky Casement
, Soraya Caixeiro
, Andrew Morton
, Gavin B. Robertson
, Paul L. Appleton
, Gareth B. Miles
, Carl S. Tucker
, Samantha J. Pitt
, Malte C. Gather

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Characterizing single cell contractility in the beating heart is strongly limited by light scattering and extreme tissue dynamics. Here, we use tissue-integrated microlasers to measure contractility in live zebrafish and living myocardial slices at a depth several times deeper than multiphoton microscopy-based techniques.

Original language	English
Title of host publication	Novel Techniques in Microscopy (NTM 2021)
Subtitle of host publication	Proceedings Biophotonics Congress 2021, 12-16 April 2021, Washington, DC, United States
Publisher	The Optical Society
Number of pages	2
ISBN (Electronic)	9781557528209
ISBN (Print)	9781943580859
Publication status	Published - 2021
Event	Novel Techniques in Microscopy, NTM 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021 - Virtual, Online, United States Duration: 12 Apr 2021 → 16 Apr 2021

Publication series

Name	Optics InfoBase Conference Papers
ISSN (Print)	2162-2701

Conference

Conference	Novel Techniques in Microscopy, NTM 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021
Country/Territory	United States
City	Virtual, Online
Period	12/04/21 → 16/04/21

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Schubert, M., Woolfson, L., Barnard, I. R. M., Dorward, A. M., Casement, B., Caixeiro, S., Morton, A., Robertson, G. B., Appleton, P. L., Miles, G. B., Tucker, C. S., Pitt, S. J., & Gather, M. C. (2021). Deep tissue contractility sensing with biointegrated microlasers. In Novel Techniques in Microscopy (NTM 2021): Proceedings Biophotonics Congress 2021, 12-16 April 2021, Washington, DC, United States Article NW3C.2 (Optics InfoBase Conference Papers). The Optical Society. https://www.osapublishing.org/abstract.cfm?uri=NTM-2021-NW3C.2

@inproceedings{6584d48d03b044d787e97cb3f7340cce,

title = "Deep tissue contractility sensing with biointegrated microlasers",

abstract = "Characterizing single cell contractility in the beating heart is strongly limited by light scattering and extreme tissue dynamics. Here, we use tissue-integrated microlasers to measure contractility in live zebrafish and living myocardial slices at a depth several times deeper than multiphoton microscopy-based techniques.",

author = "Marcel Schubert and Lewis Woolfson and Barnard, \{Isla R.M.\} and Dorward, \{Amy M.\} and Becky Casement and Soraya Caixeiro and Andrew Morton and Robertson, \{Gavin B.\} and Appleton, \{Paul L.\} and Miles, \{Gareth B.\} and Tucker, \{Carl S.\} and Pitt, \{Samantha J.\} and Gather, \{Malte C.\}",

year = "2021",

language = "English",

isbn = "9781943580859",

series = "Optics InfoBase Conference Papers",

publisher = "The Optical Society",

booktitle = "Novel Techniques in Microscopy (NTM 2021)",

address = "United States",

note = "Novel Techniques in Microscopy, NTM 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021 ; Conference date: 12-04-2021 Through 16-04-2021",

}

Schubert, M, Woolfson, L, Barnard, IRM, Dorward, AM, Casement, B, Caixeiro, S, Morton, A, Robertson, GB, Appleton, PL, Miles, GB, Tucker, CS, Pitt, SJ & Gather, MC 2021, Deep tissue contractility sensing with biointegrated microlasers. in Novel Techniques in Microscopy (NTM 2021): Proceedings Biophotonics Congress 2021, 12-16 April 2021, Washington, DC, United States., NW3C.2, Optics InfoBase Conference Papers, The Optical Society, Novel Techniques in Microscopy, NTM 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021, Virtual, Online, United States, 12/04/21. <https://www.osapublishing.org/abstract.cfm?uri=NTM-2021-NW3C.2>

Deep tissue contractility sensing with biointegrated microlasers. / Schubert, Marcel; Woolfson, Lewis; Barnard, Isla R.M. et al.
Novel Techniques in Microscopy (NTM 2021): Proceedings Biophotonics Congress 2021, 12-16 April 2021, Washington, DC, United States. The Optical Society, 2021. NW3C.2 (Optics InfoBase Conference Papers).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - Deep tissue contractility sensing with biointegrated microlasers

AU - Schubert, Marcel

AU - Woolfson, Lewis

AU - Barnard, Isla R.M.

AU - Dorward, Amy M.

AU - Casement, Becky

AU - Caixeiro, Soraya

AU - Morton, Andrew

AU - Robertson, Gavin B.

AU - Appleton, Paul L.

AU - Miles, Gareth B.

AU - Tucker, Carl S.

AU - Pitt, Samantha J.

AU - Gather, Malte C.

PY - 2021

Y1 - 2021

N2 - Characterizing single cell contractility in the beating heart is strongly limited by light scattering and extreme tissue dynamics. Here, we use tissue-integrated microlasers to measure contractility in live zebrafish and living myocardial slices at a depth several times deeper than multiphoton microscopy-based techniques.

AB - Characterizing single cell contractility in the beating heart is strongly limited by light scattering and extreme tissue dynamics. Here, we use tissue-integrated microlasers to measure contractility in live zebrafish and living myocardial slices at a depth several times deeper than multiphoton microscopy-based techniques.

UR - https://opg.optica.org/conference.cfm?meetingid=95&yr=2021

M3 - Conference contribution

AN - SCOPUS:85119685615

SN - 9781943580859

T3 - Optics InfoBase Conference Papers

BT - Novel Techniques in Microscopy (NTM 2021)

PB - The Optical Society

T2 - Novel Techniques in Microscopy, NTM 2021 - Part of Biophotonics Congress: Optics in the Life Sciences 2021

Y2 - 12 April 2021 through 16 April 2021

ER -

Deep tissue contractility sensing with biointegrated microlasers

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