Copper N-heterocyclic carbene complexes as active catalysts for the synthesis of 2-substituted oxazolines from nitriles and aminoalcohols

Michael Trose, Faima Lazreg, Mathieu Lesieur, Catherine S.J. Cazin

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)
3 Downloads (Pure)

Abstract

The reaction between nitriles and aminoalcohols to access 2-substituted oxazolines was investigated. Using copper–NHC complexes, various nitriles were successfully converted into the corresponding oxazolines, under milder and less wasteful conditions than previously reported methods.
Original languageEnglish
JournalThe Journal of Organic Chemistry
VolumeArticle ASAP
Early online date1 Oct 2015
DOIs
Publication statusPublished - 2015

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