Conventional and unconventional antimicrobials from fish, marine invertebrates and micro-algae

Valerie Jane Smith; Andrew Paul Desbois; Elisabeth Dyrynda

doi:10.3390/md8041213

Conventional and unconventional antimicrobials from fish, marine invertebrates and micro-algae

Valerie Jane Smith
, Andrew Paul Desbois
, Elisabeth Dyrynda

Research output: Contribution to journal › Article › peer-review

Abstract

All eukaryotic organisms, single-celled or multi-cellular, produce a diverse array of natural anti-infective agents that, in addition to conventional antimicrobial peptides, also include proteins and other molecules often not regarded as part of the innate defences. Examples range from histones, fatty acids, and other structural components of cells to pigments and regulatory proteins. These probably represent very ancient defence factors that have been re-used in new ways during evolution. This review discusses the nature, biological role in host protection and potential biotechnological uses of some of these compounds, focusing on those from fish, marine invertebrates and marine micro-algae.

Original language	English
Pages (from-to)	1213-1262
Journal	Marine Drugs
Volume	8
Issue number	4
DOIs	https://doi.org/10.3390/md8041213
Publication status	Published - 14 Apr 2010

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 14 Life Below Water

Keywords

Amphipathicity
Antimicrobial peptides
Fatty acids
Innate defence
Pigments

Access to Document

10.3390/md8041213

Smith2010marinedrugs 08 01213 v2
© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
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title = "Conventional and unconventional antimicrobials from fish, marine invertebrates and micro-algae",

abstract = "All eukaryotic organisms, single-celled or multi-cellular, produce a diverse array of natural anti-infective agents that, in addition to conventional antimicrobial peptides, also include proteins and other molecules often not regarded as part of the innate defences. Examples range from histones, fatty acids, and other structural components of cells to pigments and regulatory proteins. These probably represent very ancient defence factors that have been re-used in new ways during evolution. This review discusses the nature, biological role in host protection and potential biotechnological uses of some of these compounds, focusing on those from fish, marine invertebrates and marine micro-algae.",

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AU - Smith, Valerie Jane

AU - Desbois, Andrew Paul

AU - Dyrynda, Elisabeth

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Y1 - 2010/4/14

N2 - All eukaryotic organisms, single-celled or multi-cellular, produce a diverse array of natural anti-infective agents that, in addition to conventional antimicrobial peptides, also include proteins and other molecules often not regarded as part of the innate defences. Examples range from histones, fatty acids, and other structural components of cells to pigments and regulatory proteins. These probably represent very ancient defence factors that have been re-used in new ways during evolution. This review discusses the nature, biological role in host protection and potential biotechnological uses of some of these compounds, focusing on those from fish, marine invertebrates and marine micro-algae.

AB - All eukaryotic organisms, single-celled or multi-cellular, produce a diverse array of natural anti-infective agents that, in addition to conventional antimicrobial peptides, also include proteins and other molecules often not regarded as part of the innate defences. Examples range from histones, fatty acids, and other structural components of cells to pigments and regulatory proteins. These probably represent very ancient defence factors that have been re-used in new ways during evolution. This review discusses the nature, biological role in host protection and potential biotechnological uses of some of these compounds, focusing on those from fish, marine invertebrates and marine micro-algae.

KW - Amphipathicity

KW - Antimicrobial peptides

KW - Fatty acids

KW - Innate defence

KW - Pigments

UR - https://www.scopus.com/pages/publications/77952579210

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SN - 1660-3397

VL - 8

SP - 1213

EP - 1262

JO - Marine Drugs

JF - Marine Drugs

IS - 4

ER -

Conventional and unconventional antimicrobials from fish, marine invertebrates and micro-algae

Abstract

UN SDGs

Keywords

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