Clinical stringent response activation promotes conjugal transfer of staphylococcal resistance plasmids

Ashley T. Deventer; Ava Sutherland; Daria Biernacka; Paul R. Johnston; Claire E. Stevens; Anna-Karina Kaczorowska; Alisdair B. Boraston; Joanne K. Hobbs

doi:10.1101/2025.11.12.688057

Clinical stringent response activation promotes conjugal transfer of staphylococcal resistance plasmids

Ashley T. Deventer
, Ava Sutherland
, Daria Biernacka
, Paul R. Johnston
, Claire E. Stevens
, Anna-Karina Kaczorowska
, Alisdair B. Boraston
, Joanne K. Hobbs^*

^*Corresponding author for this work

Research output: Working paper › Preprint

Original language	English
Publisher	bioRxiv
Pages	1-39
Number of pages	39
DOIs	https://doi.org/10.1101/2025.11.12.688057
Publication status	Published - 12 Nov 2025

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10.1101/2025.11.12.688057Licence: CC BY

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The Role of Clinical Stringent Response: The Role of Clinical Stringent Response-Activating Mutations in Promoting Horizontal Gene Transfer and Antibiotic Resistance Dissemination
Hobbs, J. (PI)
The Royal Society
1/12/23 → 30/11/24
Project: Standard

Cite this

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title = "Clinical stringent response activation promotes conjugal transfer of staphylococcal resistance plasmids",

author = "Deventer, \{Ashley T.\} and Ava Sutherland and Daria Biernacka and Johnston, \{Paul R.\} and Stevens, \{Claire E.\} and Anna-Karina Kaczorowska and Boraston, \{Alisdair B.\} and Hobbs, \{Joanne K.\}",

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AU - Sutherland, Ava

AU - Biernacka, Daria

AU - Johnston, Paul R.

AU - Stevens, Claire E.

AU - Kaczorowska, Anna-Karina

AU - Boraston, Alisdair B.

AU - Hobbs, Joanne K.

PY - 2025/11/12

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DO - 10.1101/2025.11.12.688057

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BT - Clinical stringent response activation promotes conjugal transfer of staphylococcal resistance plasmids

PB - bioRxiv

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Clinical stringent response activation promotes conjugal transfer of staphylococcal resistance plasmids

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The Role of Clinical Stringent Response: The Role of Clinical Stringent Response-Activating Mutations in Promoting Horizontal Gene Transfer and Antibiotic Resistance Dissemination

Cite this