Abstract
Addition of Grignard and organolithium reagents to O-(1-phenylethyl) aldoximes in the presence of boron trifluoride etherate gives secondary hydroxylamines in 21-84% yield with up to 95% diastereomeric excess.
Original language | English |
---|---|
Pages (from-to) | 11473-11488 |
Number of pages | 16 |
Journal | Tetrahedron |
Volume | 51 |
Issue number | 42 |
Publication status | Published - 16 Oct 1995 |
Keywords
- ALDEHYDE-SAMP HYDRAZONES
- ALPHA-IMINO ESTERS
- SODIUM-BOROHYDRIDE
- ORGANOLITHIUM REAGENTS
- AMINO-ACIDS
- ETHERS
- REDUCTION
- CHLORIDE