Chemical genetics: how does it function?

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

This article highlights recent successes in the field of chemical genetics. It discusses the challenges inherent in this interdisciplinary research field and focuses on the essential role that the biologically aware synthetic chemist can play.

Original languageEnglish
Pages (from-to)2761-2774
Number of pages14
JournalPhilosophical Transactions of the Royal Society. A, Mathematical, Physical and Engineering Sciences
Volume362
Issue number1825
DOIs
Publication statusPublished - 15 Dec 2004

Keywords

  • chemical genetics/ genomics
  • synthetic chemistry
  • diversity-oriented synthesis
  • phenotype screening
  • chemistry-biology interface
  • drug discovery
  • DIVERSITY-ORIENTED SYNTHESIS
  • SMALL-MOLECULE INHIBITOR
  • ORGANIC-SYNTHESIS
  • MYOSIN-II
  • PROTEIN
  • IDENTIFICATION
  • DISCOVERY
  • REVEALS
  • KINESIN
  • BIOLOGY

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