Abstract
This article highlights recent successes in the field of chemical genetics. It discusses the challenges inherent in this interdisciplinary research field and focuses on the essential role that the biologically aware synthetic chemist can play.
Original language | English |
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Pages (from-to) | 2761-2774 |
Number of pages | 14 |
Journal | Philosophical Transactions of the Royal Society. A, Mathematical, Physical and Engineering Sciences |
Volume | 362 |
Issue number | 1825 |
DOIs | |
Publication status | Published - 15 Dec 2004 |
Keywords
- chemical genetics/ genomics
- synthetic chemistry
- diversity-oriented synthesis
- phenotype screening
- chemistry-biology interface
- drug discovery
- DIVERSITY-ORIENTED SYNTHESIS
- SMALL-MOLECULE INHIBITOR
- ORGANIC-SYNTHESIS
- MYOSIN-II
- PROTEIN
- IDENTIFICATION
- DISCOVERY
- REVEALS
- KINESIN
- BIOLOGY