Changing the Regioselectivity of the Tryptophan 7-Halogenase PrnA by Site-Directed Mutagenesis

Alexander Lang; Stefan Polnick; Tristan Nicke; Peter William; Eugenio P. Patallo; James H. Naismith; Karl-Heinz van Pee

doi:10.1002/anie.201007896

Changing the Regioselectivity of the Tryptophan 7-Halogenase PrnA by Site-Directed Mutagenesis

Alexander Lang, Stefan Polnick, Tristan Nicke, Peter William, Eugenio P. Patallo, James H. Naismith, Karl-Heinz van Pee

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	2951-2953
Number of pages	3
Journal	Angewandte Chemie International Edition
Volume	50
Issue number	13
DOIs	https://doi.org/10.1002/anie.201007896
Publication status	Published - 2011

Keywords

PSEUDOMONAS-FLUORESCENS
ENZYMATIC CHLORINATION
DEPENDENT HALOGENASES
CHLOROPEROXIDASE
HALOPEROXIDASES
BIOSYNTHESIS
MECHANISM

Access to Document

10.1002/anie.201007896

bb/c000080/1: The pyrrolnitrin biosynthetic pathway
Naismith, J. (PI)
BBSRC
1/01/05 → 1/05/10
Project: Standard

Cite this

@article{299c944bf4d448c69a29c75f13209f0b,

title = "Changing the Regioselectivity of the Tryptophan 7-Halogenase PrnA by Site-Directed Mutagenesis",

keywords = "PSEUDOMONAS-FLUORESCENS, ENZYMATIC CHLORINATION, DEPENDENT HALOGENASES, CHLOROPEROXIDASE, HALOPEROXIDASES, BIOSYNTHESIS, MECHANISM",

author = "Alexander Lang and Stefan Polnick and Tristan Nicke and Peter William and Patallo, {Eugenio P.} and Naismith, {James H.} and {van Pee}, Karl-Heinz",

year = "2011",

doi = "10.1002/anie.201007896",

language = "English",

volume = "50",

pages = "2951--2953",

journal = "Angewandte Chemie International Edition",

issn = "1433-7851",

publisher = "John Wiley & Sons, Ltd",

number = "13",

}

TY - JOUR

T1 - Changing the Regioselectivity of the Tryptophan 7-Halogenase PrnA by Site-Directed Mutagenesis

AU - Lang, Alexander

AU - Polnick, Stefan

AU - Nicke, Tristan

AU - William, Peter

AU - Patallo, Eugenio P.

AU - Naismith, James H.

AU - van Pee, Karl-Heinz

PY - 2011

Y1 - 2011

KW - PSEUDOMONAS-FLUORESCENS

KW - ENZYMATIC CHLORINATION

KW - DEPENDENT HALOGENASES

KW - CHLOROPEROXIDASE

KW - HALOPEROXIDASES

KW - BIOSYNTHESIS

KW - MECHANISM

U2 - 10.1002/anie.201007896

DO - 10.1002/anie.201007896

M3 - Article

SN - 1433-7851

VL - 50

SP - 2951

EP - 2953

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

IS - 13

ER -

Changing the Regioselectivity of the Tryptophan 7-Halogenase PrnA by Site-Directed Mutagenesis

Keywords

Access to Document

Projects

bb/c000080/1: The pyrrolnitrin biosynthetic pathway

Cite this