Calpain 3 deficiency is associated with myonuclear apoptosis and profound perturbation of the IkBa/NF-kB pathway in limb girdle muscular dystrophy type 2A

S Baghdiguian, M Martin, I Richard, F Pons, C Astier, N Bourg, Ronald Thomas Hay, R Chemaly, G Halaby, J Loiselet, LV Anderson, A Lopez de Munain, M Fardeau, P Mangeat, JS Beckmann, G Lefranc

Research output: Contribution to journalArticlepeer-review

239 Citations (Scopus)
Original languageEnglish
Pages (from-to)503-511
Number of pages9
JournalNature Medicine
Volume5
Issue number5
DOIs
Publication statusPublished - May 1999

Keywords

  • MUSCLE-SPECIFIC CALPAIN
  • NUCLEAR-LOCALIZATION
  • DNA-FRAGMENTATION
  • EXPRESSION
  • PROTEIN
  • ACTIVATION
  • BCL-2
  • DOMAIN
  • VITRO
  • GENE

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