Abstract
Many bioinspired transition-metal catalysts have been developed over the recent years. In this review the progress in the design and application of ligand systems based on peptides and DNA and the development of artificial metalloenzymes are reviewed with a particular emphasis on the combination of phosphane ligands with powerful molecular recognition and shape selectivity of biomolecules. The various approaches for the assembly of these catalytic systems will be highlighted, and the possibilities that the use of the building blocks of Nature provide for catalyst optimisation strategies are discussed.
Original language | English |
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Pages (from-to) | 4680-4698 |
Number of pages | 19 |
Journal | Chemistry - A European Journal |
Volume | 17 |
Issue number | 17 |
DOIs | |
Publication status | Published - Apr 2011 |
Keywords
- CHIRAL PHOSPHINE-LIGANDS
- artificial metalloenzymes
- TRANSITION-METAL COMPLEXES
- COMPUTATIONAL ENZYME DESIGN
- phosphane ligands
- DNAzymes
- HUMAN SERUM-ALBUMIN
- SUBSTITUTED CARBONIC-ANHYDRASE
- ASYMMETRIC ALLYLIC ALKYLATION
- CONTAINING AMINO-ACIDS
- homogeneous catalysis
- ligand design
- BIOTIN-AVIDIN TECHNOLOGY
- DIELS-ALDER REACTION
- SOLID-PHASE SYNTHESIS