Bacteria SAVED from viruses

Malcolm F. White

doi:10.1016/j.cell.2020.06.015

Bacteria SAVED from viruses

Malcolm F. White^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Increasingly, cyclic nucleotide second messengers are implicated in antiviral defense systems in bacteria and archaea as well as in eukaryotes. In this issue of Cell, Lowey et al. describe SAVED—a widespread, uncharacterized cyclic nucleotide sensor protein domain that activates cell defense systems. The structure of SAVED reveals links to the CRISPR system, which also generates cyclic nucleotides in response to viral infection.

Original language	English
Pages (from-to)	5-6
Number of pages	2
Journal	Cell
Volume	182
Issue number	1
DOIs	https://doi.org/10.1016/j.cell.2020.06.015
Publication status	Published - 9 Jul 2020

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10.1016/j.cell.2020.06.015

White-2020-Bacteria-SAVED-from-viruses-Cell-AAM
Copyright © 2020 Elsevier Inc. This work has been made available online in accordance with publisher policies or with permission. Permission for further reuse of this content should be sought from the publisher or the rights holder. This is the author created accepted manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://doi.org/10.1016/j.cell.2020.06.015
Accepted author manuscript, 857 KBLicence: CC BY-NC-ND

https://www.cell.com/cell/fulltext/S0092-8674(20)30746-7

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Bacteria SAVED from viruses

Abstract

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